BMRB Entry 4924

Title:
Interactions of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (SqKv1A).
Deposition date:
2000-12-13
Original release date:
2002-04-03
Authors:
Ellis, K.; Tenenholz, T.; Gilly, W.; Blaustein, M.; Weber, D.
Citation:

Citation: Ellis, K.; Tenenholz, T.; Gilly, W.; Blaustein, M.; Weber, D.. "Interactions of a toxin from the scorpion Tityus serrulatus with a cloned K+ channel from squid (SqKv1A)."  Biochemistry 40, 5942-5953 (2001).

Assembly members:

Assembly members:
Tityustoxin K-alpha, polymer, 37 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Brazilian scorpion   Taxonomy ID: 6887   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Tityus Serrulatus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: PSR9

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Tityustoxin K-alpha: VFINAKCRGSPECLPKCKEA IGKAAGKCMNGKCKCYP

Data sets:
Data typeCount
1H chemical shifts240

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Tityustoxin K-alpha1

Entities:

Entity 1, Tityustoxin K-alpha 37 residues - Formula weight is not available

1   VALPHEILEASNALALYSCYSARGGLYSER
2   PROGLUCYSLEUPROLYSCYSLYSGLUALA
3   ILEGLYLYSALAALAGLYLYSCYSMETASN
4   GLYLYSCYSLYSCYSTYRPRO

Samples:

sample_1: Tityustoxin K-alpha 4.53 mM

sample_cond_1: ionic strength: 1.44 mM; pH: 3.50; pressure: 1 atm; temperature: 310.00 K

Experiments:

NameSampleSample stateSample conditions
NOESYnot availablenot availablenot available
TOCSYnot availablenot availablenot available
DQF-COSYnot availablenot availablenot available
ROESYnot availablenot availablenot available
P.E.COSYnot availablenot availablenot available

Software:

X-PLOR v3.1 - REFINEMENT, STRUCTURE SOLUTION

NMR spectrometers:

  • Bruker DMX 600 MHz

Related Database Links:

PDB
SWISS-PROT P46114