BMRB Entry 4741

Title:
Structure and folding of Glucagon-like Peptide 1-7-(7-36)-amide in aqueous trifluoroethanol studied by NMR
Deposition date:
2000-05-22
Original release date:
2002-04-08
Authors:
Chang, Xiaoqing; Keller, D.; Bjorn, s.; Led, Jens
Citation:

Citation: Chang, Xiaoqing; Keller, D; Bjorn, S.; Led, Jens. "Structure and folding of Glucagon-like Peptide 1-7-(7-36)-amide in aqueous trifluoroethanol studied by NMR"  Magn. Reson. Chem. 39, 477-483 (2001).

Assembly members:

Assembly members:
Glucogen-like peptide-1-(7-36)-amide, polymer, 30 residues, 3300 Da.

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Experimental source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Glucogen-like peptide-1-(7-36)-amide: HAEGTFTSDVSSYLEGQAAK EFIAWLVKGR

Data typeCount
1H chemical shifts1512

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1GLP-11

Entities:

Entity 1, GLP-1 30 residues - 3300 Da.

1   HISALAGLUGLYTHRPHETHRSERASPVAL
2   SERSERTYRLEUGLUGLYGLNALAALALYS
3   GLUPHEILEALATRPLEUVALLYSGLYARG

Samples:

sample_1: Glucogen-like peptide-1-(7-36)-amide 1.4 mM

sample_2: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 4.62%

sample_3: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 8.82%

sample_4: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 13.89%

sample_5: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 19.48%

sample_6: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 24.39%

sample_7: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 29.55%

sample_8: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 34.74%

sample_9: Glucogen-like peptide-1-(7-36)-amide 1.4 mM; 2,2,2-trifluoroethanol-d3 50%

cond-1: pH*: 2.50; temperature: 300 K

Experiments:

NameSampleSample stateSample conditions
PFG self-diffusion experiment with water-sLED pulsenot availablenot availablenot available
NOESYnot availablenot availablenot available
TOCSYnot availablenot availablenot available

Software:

No software information available

NMR spectrometers:

  • Varian Inova Plus 500 MHz
  • Varian Inova Plus 750 MHz
  • Bruker AM 500 MHz

Related Database Links:

PDB
DBJ BAA00010 BAM48567
GB AAA30538 AAA37074 AAA40588 AAA41235 AAI02222
PIR GCPG
PRF 0905236A
REF NP_001003044 NP_001166423 NP_036839 NP_776341 NP_999489
SP P01272 P01273 P01274 P05110 P06883
TPG DAA32664
AlphaFold P01274