BMRB Entry 34725
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PDB ID: 7zew
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR34725
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Blatter, Markus; Meylan, Charlotte; Clery, Antoine; Giambruno, Roberto; Nikolaev, Yaroslav; Heidecker, Michel; Solanki, Jessica Arvindbhai; Diaz, Manuel; Gabellini, Davide; Allain, Frederic H-T. "RNA binding induces an allosteric switch in Cyp33 to repress MLL1-mediated transcription" Sci. Adv. 9, eadf5330-eadf5330 (2023).
PubMed: 37075125
Assembly members:
entity_1, polymer, 117 residues, 13189.849 Da.
entity_2, polymer, 6 residues, 1907.237 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: PTYB12
Entity Sequences (FASTA):
entity_1: AGHMATTKRVLYVGGLAEEV
DDKVLHAAFIPFGDITDIQI
PLDYETEKHRGFAFVEFELA
EDAAAAIDNMNESELFGRTI
RVNLAKPMRIKEGSSRPVWS
DDDWLKKFSGKTLEENK
entity_2: AAUAAA
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 430 |
| 15N chemical shifts | 113 |
| 1H chemical shifts | 855 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | unit_1 | 1 |
| 2 | unit_2 | 2 |
Entities:
Entity 1, unit_1 117 residues - 13189.849 Da.
| 1 | ALA | GLY | HIS | MET | ALA | THR | THR | LYS | ARG | VAL | ||||
| 2 | LEU | TYR | VAL | GLY | GLY | LEU | ALA | GLU | GLU | VAL | ||||
| 3 | ASP | ASP | LYS | VAL | LEU | HIS | ALA | ALA | PHE | ILE | ||||
| 4 | PRO | PHE | GLY | ASP | ILE | THR | ASP | ILE | GLN | ILE | ||||
| 5 | PRO | LEU | ASP | TYR | GLU | THR | GLU | LYS | HIS | ARG | ||||
| 6 | GLY | PHE | ALA | PHE | VAL | GLU | PHE | GLU | LEU | ALA | ||||
| 7 | GLU | ASP | ALA | ALA | ALA | ALA | ILE | ASP | ASN | MET | ||||
| 8 | ASN | GLU | SER | GLU | LEU | PHE | GLY | ARG | THR | ILE | ||||
| 9 | ARG | VAL | ASN | LEU | ALA | LYS | PRO | MET | ARG | ILE | ||||
| 10 | LYS | GLU | GLY | SER | SER | ARG | PRO | VAL | TRP | SER | ||||
| 11 | ASP | ASP | ASP | TRP | LEU | LYS | LYS | PHE | SER | GLY | ||||
| 12 | LYS | THR | LEU | GLU | GLU | ASN | LYS |
Entity 2, unit_2 6 residues - 1907.237 Da.
| 1 | A | A | U | A | A | A |
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CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks