BMRB Entry 34243

Name: Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor
Published: 2018-10-19

Click here to enlarge.

PDB ID: 6fwn
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR34243
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

Select model:

I am color blind

Download raw data. Direct link to this display. Help

Title:

Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor

Deposition date:

2018-03-06

Original release date:

2018-10-19

Authors:

Xu, E.; von Buelow, S.; Chen, P.; Lenting, P.; Kolsek, K.; Aponte-Santamaria, C.; Simon, B.; Foot, J.; Obser, T.; Graeter, F.; Schneppenheim, R.; Denis, C.; Wilmanns, M.; Hennig, J.

Citation:

Citation: Xu, E.; von Bulow, S.; Chen, P.; Lenting, P.; Kolsek, K.; Aponte-Santamaria, C.; Simon, B.; Foot, J.; Obser, T.; Schneppenheim, R.; Grater, F.; Denis, C.; Wilmanns, M.; Hennig, J.. "Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor." Blood 133, 366-376 (2019).
PubMed: 30305279

Assembly members:

Assembly members:
entity_1, polymer, 85 residues, 9122.324 Da.

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli BL21(DE3) Vector: pHAT3

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GSMASACEVVTGSPRGDSQS SWKSVGSQWASPENPCLINE CVRVKEEVFIQQRNVSCPQL EVPVCPSGFQLSCKTSACCP SCRCE

Data sets:

assigned_chemical_shifts
- assigned_chemical_shifts_1
spectral_peak_list

Data type	Count
13C chemical shifts	318
15N chemical shifts	84
1H chemical shifts	514

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
Hide all

Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	entity_1	1

Entities:

Entity 1, entity_1 85 residues - 9122.324 Da.

1

GLY

SER

MET

ALA

SER

ALA

CYS

GLU

VAL

2

THR

GLY

SER

PRO

ARG

GLY

ASP

SER

GLN

SER

3

SER

TRP

LYS

SER

VAL

GLY

SER

GLN

TRP

ALA

4

SER

PRO

GLU

ASN

PRO

CYS

LEU

ILE

ASN

GLU

5

CYS

VAL

ARG

VAL

LYS

GLU

VAL

PHE

ILE

6

GLN

ARG

ASN

VAL

SER

CYS

PRO

GLN

LEU

7

GLU

VAL

PRO

VAL

CYS

PRO

SER

GLY

PHE

GLN

8

LEU

SER

CYS

LYS

THR

SER

ALA

CYS

PRO

9

SER

CYS

ARG

CYS

GLU

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aliphatic	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aromatic	sample_1	isotropic	sample_conditions_1
2D 1H-13C HMQC	sample_1	isotropic	sample_conditions_1
3D HNCA	sample_1	isotropic	sample_conditions_1
3D HNCO	sample_1	isotropic	sample_conditions_1
3D C(CO)NH	sample_1	isotropic	sample_conditions_1
3D H(CCO)NH	sample_1	isotropic	sample_conditions_1
3D HBHA(CO)NH	sample_1	isotropic	sample_conditions_1
3D CBCA(CO)NH	sample_1	isotropic	sample_conditions_1
3D HNCACB	sample_1	isotropic	sample_conditions_1
3D HCCH-TOCSY	sample_1	isotropic	sample_conditions_1
3D 1H-13C NOESY-HSQC	sample_1	isotropic	sample_conditions_1
3D 1H-15N NOESY-HSQC	sample_1	isotropic	sample_conditions_1
3D HCCH-TOCSY	sample_1	isotropic	sample_conditions_1
3D 1H-13C HMQC-NOESY	sample_2	isotropic	sample_conditions_1
3D 1H-13C HMQC-NOESY aromatic	sample_2	isotropic	sample_conditions_1

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks

BMRB Entry 34243

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers: