BMRB Entry 31154
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR31154
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
All files associated with the entry
Citation: Liu, W.; Zhu, B.; Liu, L.; Xia, X.; Jang, J.; Dickerhoff, J.; Yang, D.; Mao, Z.. "Solution structures and effects of a platinum compound successively bound MYC G-quadruplex." Nucleic Acids Res. 52, 9397-9406 (2024).
PubMed: 39077944
Assembly members:
entity_1, polymer, 19 residues, 6070.918 Da.
entity_2, non-polymer, 555.489 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Homo sapiens
Entity Sequences (FASTA):
entity_1: TAGGGAGGGTAGGGAGGGT
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 193 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | unit_1 | 1 |
| 2 | unit_2 | 2 |
Entities:
Entity 1, unit_1 19 residues - 6070.918 Da.
| 1 | DT | DA | DG | DG | DG | DA | DG | DG | DG | DT | ||||
| 2 | DA | DG | DG | DG | DA | DG | DG | DG | DT |
Entity 2, unit_2 - C24 H16 N4 Pt - 555.489 Da.
| 1 | H9C |
Samples:
sample_1: Myc1234 G4 800 uM; Pt-phen 800 uM
sample_conditions_1: ionic strength: 10 mM; pH: 7; pressure: 1 atm; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| 2D NOESY | sample_1 | anisotropic | sample_conditions_1 |
| 2D TOCSY | sample_1 | anisotropic | sample_conditions_1 |
| 2D COSY | sample_1 | anisotropic | sample_conditions_1 |
Software:
Sparky, Goddard - chemical shift assignment, peak picking
X-PLOR NIH, X-PLOR NIH - structure calculation
Discovery Studio, Discovery - refinement
NMR spectrometers:
- Bruker AVANCE 600 MHz