BMRB Entry 30846

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PDB ID: 7lgl
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30846
MolProbity Validation Chart

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Title:
Structural characterization of two b-KTx scorpion toxins. One of them blocks human KCNQ1 potassium channels
Deposition date:
2021-01-20
Original release date:
2021-12-31
Authors:
del Rio-Portilla, F.; Lopez-Giraldo, A.
Citation:

Citation: Titaux-Delgado, G.; Lopez-Giraldo, A.; Carrillo, E.; Cofas-Vargas, L.; Carranza-Gonzalez, L.; Lopez-Vera, E.; Garcia-Hernandez, E.; del Rio-Portilla, J.. "Beta-KTx14.3, a scorpion toxin, blocks the human potassium channel KCNQ1"  Biochim. Biophys. Acta Proteins Proteom. 1871, 140906-140906 (2023).
PubMed: 36918120

Assembly members:

Assembly members:
entity_1, polymer, 47 residues, 5294.156 Da.

Natural source:

Natural source:   Common Name: Brazilian scorpion   Taxonomy ID: 309814   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Tityus costatus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli BL21(DE3)

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: KIKSGWERLTSESEYACPAI DKFCEDHCAAKKAVGKCDDF KCNCIKL

Data sets:
Data typeCount
1H chemical shifts300

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11

Entities:

Entity 1, unit_1 47 residues - 5294.156 Da.

1   LYSILELYSSERGLYTRPGLUARGLEUTHR
2   SERGLUSERGLUTYRALACYSPROALAILE
3   ASPLYSPHECYSGLUASPHISCYSALAALA
4   LYSLYSALAVALGLYLYSCYSASPASPPHE
5   LYSCYSASNCYSILELYSLEU