BMRB Entry 30652

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PDB ID: 6q2i
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30652
MolProbity Validation Chart

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Title:
Human CstF-64 RRM
Deposition date:
2019-08-08
Original release date:
2020-08-03
Authors:
Latham, M.; Masoumzadeh, E.
Citation:

Citation: Grozdanov, Petar; Masoumzadeh, Elahe; Kalscheuer, Vera; Bienvenu, Thierry; Billuart, Pierre; Delrue, Marie-Ange; Latham, Michael; MacDonald, Clinton. "A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans"  Nucleic Acids Res. 48, 9804-9821 (2020).
PubMed: 32816001

Assembly members:

Assembly members:
entity_1, polymer, 108 residues, 11965.345 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET22

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: MAGLTVRDPAVDRSLRSVFV GNIPYEATEEQLKDIFSEVG PVVSFRLVYDRETGKPKGYG FCEYQDQETALSAMRNLNGR EFSGRALRVDNAASEKNKEE LKSLGTGA

Data sets:
Data typeCount
13C chemical shifts241
15N chemical shifts102
1H chemical shifts101

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 108 residues - 11965.345 Da.

1   METALAGLYLEUTHRVALARGASPPROALA
2   VALASPARGSERLEUARGSERVALPHEVAL
3   GLYASNILEPROTYRGLUALATHRGLUGLU
4   GLNLEULYSASPILEPHESERGLUVALGLY
5   PROVALVALSERPHEARGLEUVALTYRASP
6   ARGGLUTHRGLYLYSPROLYSGLYTYRGLY
7   PHECYSGLUTYRGLNASPGLNGLUTHRALA
8   LEUSERALAMETARGASNLEUASNGLYARG
9   GLUPHESERGLYARGALALEUARGVALASP
10   ASNALAALASERGLULYSASNLYSGLUGLU
11   LEULYSSERLEUGLYTHRGLYALA

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