BMRB Entry 30545

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PDB ID: 6n8c
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30545
MolProbity Validation Chart

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Title:
Structure of the Huttingtin tetramer/dimer mixture determined by paramagnetic NMR
Deposition date:
2018-11-29
Original release date:
2019-02-08
Authors:
Schwieters, C.; Kotler, S.; Schmidt, T.; Ceccon, A.; Ghirlando, R.; Libich, D.; Clore, G.
Citation:

Citation: Kotler, S.; Tugarinov, V.; Schmidt, T.; Ceccon, A.; Libich, D.; Ghirlando, R.; Schwieters, C.; Clore, G.. "Probing initial transient oligomerization events facilitating Huntingtin fibril nucleation at atomic resolution by relaxation-based NMR"  Proc. Natl. Acad. Sci. U.S.A. 116, 3562-3571 (2019).
PubMed: 30808748

Assembly members:

Assembly members:
entity_1, polymer, 23 residues, 2743.116 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: ATLEKLMKAFESLKSFQQQQ QQQ

Data sets:
Data typeCount
13C chemical shifts21
15N chemical shifts16

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_1, 11
2entity_1, 21
3entity_1, 31
4entity_1, 41

Entities:

Entity 1, entity_1, 1 23 residues - 2743.116 Da.

1   ALATHRLEUGLULYSLEUMETLYSALAPHE
2   GLUSERLEULYSSERPHEGLNGLNGLNGLN
3   GLNGLNGLN