BMRB Entry 30367

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PDB ID: 6bgg
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR30367
MolProbity Validation Chart

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Title:
Solution NMR structures of the BRD3 ET domain in complex with a CHD4 peptide
Deposition date:
2017-10-28
Original release date:
2018-03-14
Authors:
Wai, D.; Szyszka, T.; Campbell, A.; Kwong, C.; Wilkinson-White, L.; Silva, A.; Low, J.; Kwan, A.; Gamsjaeger, R.; Lu, B.; Vakoc, C.; Blobel, G.; Mackay, J.
Citation:

Citation: Wai, Dorothy; Szyszka, Taylor; Campbell, Amy; Kwong, Cherry; Wilkinson-White, Lorna; Silva, Ana; Low, Jason; Kwan, Ann; Gamsjaeger, Roland; Chalmers, James; Patrick, Wayne; Lu, Bin; Vakoc, Christopher; Blobel, Gerd; Mackay, Joel. "The BRD3 ET domain recognizes a short peptide motif through a mechanism that is conserved across chromatin remodelers and transcriptional regulators"  J. Biol. Chem. 293, 7160-7175 (2018).
PubMed: 29567837

Assembly members:

Assembly members:
entity_1, polymer, 12 residues, 1273.629 Da.
entity_2, polymer, 93 residues, 10687.956 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: KVAPLKIKLGGF
entity_2: GPLGSASASYDSEEEEEGLP MSYDEKRQLSLDINRLPGEK LGRVVHIIQSREPSLRDSNP DEIEIDFETLKPTTLRELER YVKSCLQKKQRKP

Data typeCount
13C chemical shifts354
15N chemical shifts82
1H chemical shifts603

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11
2entity_22

Entities:

Entity 1, entity_1 12 residues - 1273.629 Da.

1   LYSVALALAPROLEULYSILELYSLEUGLY
2   GLYPHE

Entity 2, entity_2 93 residues - 10687.956 Da.

1   GLYPROLEUGLYSERALASERALASERTYR
2   ASPSERGLUGLUGLUGLUGLUGLYLEUPRO
3   METSERTYRASPGLULYSARGGLNLEUSER
4   LEUASPILEASNARGLEUPROGLYGLULYS
5   LEUGLYARGVALVALHISILEILEGLNSER
6   ARGGLUPROSERLEUARGASPSERASNPRO
7   ASPGLUILEGLUILEASPPHEGLUTHRLEU
8   LYSPROTHRTHRLEUARGGLULEUGLUARG
9   TYRVALLYSSERCYSLEUGLNLYSLYSGLN
10   ARGLYSPRO

Download HSQC peak lists in one of the following formats:
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SPARKY: Backbone or all simulated peaks