BMRB

Biological Magnetic Resonance Data Bank


A Repository for Data from NMR Spectroscopy on Proteins, Peptides, Nucleic Acids, and other Biomolecules
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BMRB Entry 26674

Title: Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ   PubMed: 26817840

Deposition date: 2015-09-30 Original release date: 2015-09-30

Authors: Green, Brad; ., Chhabra; S., .

Citation: Green, Brad; ., Gajewiak; ., .; ., J.; ., .; 26674, .; 8, 26674; Raymond, 9. "Structural basis for the inhibition of voltage-gated sodium channels with conotoxin-muOxi-GVIIJ"  J. Biol. Chem. 291, 7205-7220 (2016).

Assembly members:
GVIIJ_C24S, polymer, 35 residues, Formula weight is not available

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):
GVIIJ_C24S: GWCGDXGATCGKLRLYCCSG FCDSYTKTCKDKSSA

Data sets:
Data typeCount
13C chemical shifts63
311H chemical shifts

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1GVIIJ[C24S]1

Entities:

Entity 1, GVIIJ[C24S] 35 residues - Formula weight is not available

1   GLY.266745.GLY.2667411.
2   LEU.2667417.SER.2667423.
3   TYR.2667429.ASP.2667435

Samples:

sample_1: GVIIJ_C24S 1.4 mM; natural abundance; .

sample_conditions_1: ionic strength: 10 mM; 3.2: . 26674; .: atm temperature; K: 26674

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
nosotropicnot availablenot available
not availablenot availablenot availablenot available
not availablenot available1not available
not availablenot available$sample_conditions_1not available

Software:

CcpNmr v2.1.5, CCPN - chemical shift assignment, 26674

NMR spectrometers:

  • Bruker Avance 600 MHz
  • Varian INOVA 600 MHz