BMRB Entry 26035
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PDB ID: 2nct
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR26035
MolProbity Validation Chart
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NMR-STAR v3 text file.
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Citation: Rujas, Edurne; Partida-Hanon, Angelica; Gulzar, Naveed; Morante, Koldo; Apellaniz, Beatriz; Garcia-Porras, Miguel; Bruix, Marta; Tsumoto, Kouhei; Scott, Jamie; Jimenez, M. Angeles; Caaveiro, Jose; Nieva, Jose. "Structural basis for broad neutralization of HIV-1 through the molecular recognition of 10E8 helical epitope at the membrane interface" Sci Rep 6, 38177-38177 (2016).
PubMed: 27905530
Assembly members:
10E8p, polymer, 36 residues, 4624.739 Da.
Natural source: Common Name: HIV-1 Taxonomy ID: 11676 Superkingdom: Viruses Kingdom: not available Genus/species: Lintivirus not available
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
10E8p: KKKKDKWASLWNWFDITNWL
WYIKLFIMIVGKKKKK
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 100 |
| 1H chemical shifts | 493 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | 10E8p | 1 |
Entities:
Entity 1, 10E8p 36 residues - 4624.739 Da.
The sequence DKWASLWNWFDITNWLWYIKLFIMIVG to residues 664-690 of glycoprotein gp41 from HIV. The four N-terminal (KKKK) and the five C-terminal residues (KKKKK) were added to the native sequence to improve peptide solubility.
| 1 | LYS | LYS | LYS | LYS | ASP | LYS | TRP | ALA | SER | LEU | ||||
| 2 | TRP | ASN | TRP | PHE | ASP | ILE | THR | ASN | TRP | LEU | ||||
| 3 | TRP | TYR | ILE | LYS | LEU | PHE | ILE | MET | ILE | VAL | ||||
| 4 | GLY | LYS | LYS | LYS | LYS | LYS |