BMRB Entry 25517
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PDB ID:
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR25517
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Hoang, Huy; Song, Kun; Hill, Timothy; Derksen, David; Edmonds, David; Kok, W. Mei; Limberakis, Chris; Liras, Spiros; Loria, Paula; Mascitti, Vincent; Mathiowetz, Alan; Mitchell, Justin; Piotrowski, David; Price, David; Stanton, Robert; Suen, Jacky; Withka, Jane; Griffith, David; Fairlie, David. "Short hydrophobic peptides with cyclic constraints are potent glucagon-like peptide-1 receptor (GLP-1R) agonists" J. Med. Chem. 58, 4080-4085 (2015).
PubMed: 25839426
Assembly members:
entity, polymer, 12 residues, 1259.314 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: chemical synthesis
Entity Sequences (FASTA):
entity: HAEGTFTSDFFX
- assigned_chemical_shifts
| Data type | Count |
| 1H chemical shifts | 20 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | entity | 1 |
Entities:
Entity 1, entity 12 residues - 1259.314 Da.
| 1 | HIS | ALA | GLU | GLY | THR | PHE | THR | SER | ASP | PHE | ||||
| 2 | PHE | NH2 |
Samples:
sample_1: entity 1 mM
sample_conditions_1: ionic strength: 0.01 M; pH: 7; pressure: 1 atm; temperature: 298 K
Experiments:
| Name | Sample | Sample state | Sample conditions |
|---|---|---|---|
| NOESY | sample_1 | isotropic | sample_conditions_1 |
Software:
xplor, Brunger - structure solution
NMR spectrometers:
- Bruker Avance 600 MHz