BMRB Entry 25142

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PDB ID: 2msy
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR25142
MolProbity Validation Chart

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Title:
Solution structure of Hox homeodomain
Deposition date:
2014-08-11
Original release date:
2015-09-14
Authors:
Kim, Hyun-Hwi; Park, Sung Jean; Han, Jung-Hwa; Lee, Bong-Jin
Citation:

Citation: Kim, Hyun-Hwi; Park, Sung Jean; Han, Jung-Hwa; Pathak, Chinar; Cheong, Hae-Kap; Lee, Bong-Jin. "Structural insight into the interaction between the Hox and HMGB1 and understanding of the HMGB1-enhancing effect of Hox-DNA binding"  Biochim. Biophys. Acta 1854, 449-459 (2015).
PubMed: 25707357

Assembly members:

Assembly members:
entity, polymer, 68 residues, 8677.323 Da.

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28a (+)

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: ANWIHARSTRKKRCPYTKYQ TLELEKEFLFNMYLTRDRRY EVARVLNLTERQVKIWFQNR RMKMKKMN

Data sets:
Data typeCount
13C chemical shifts285
15N chemical shifts71
1H chemical shifts417

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
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Assembly:

Entity Assembly IDEntity NameEntity ID
1Hox homeodomain1

Entities:

Entity 1, Hox homeodomain 68 residues - 8677.323 Da.

1   ALAASNTRPILEHISALAARGSERTHRARG
2   LYSLYSARGCYSPROTYRTHRLYSTYRGLN
3   THRLEUGLULEUGLULYSGLUPHELEUPHE
4   ASNMETTYRLEUTHRARGASPARGARGTYR
5   GLUVALALAARGVALLEUASNLEUTHRGLU
6   ARGGLNVALLYSILETRPPHEGLNASNARG
7   ARGMETLYSMETLYSLYSMETASN

Related Database Links:

BMRB 17407
PDB 2LP0 2MSY
DBJ BAA86253 BAB28077 BAC37378 BAE22140 BAE26045
EMBL CAA30487 CAA33528 CAA39026 CAA42016 CAA44542
GB AAA37856 AAB04756 AAB68680 AAD15960 AAD15961
PIR C45187 D45187
REF NP_001017256 NP_001094377 NP_001132998 NP_001133005 NP_001133012
SP B5DFK3 O42502 P09633 P28356 P28357
TPG DAA30041 DAA32777
AlphaFold B5DFK3 O42502 P09633 P28356 P28357

Download HSQC peak lists in one of the following formats:
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