BMRB Entry 21018

Name: Compstatin 10
Published: 2012-11-02

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR21018

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

Select model:

I am color blind

Download raw data. Direct link to this display. Help

Title:

Compstatin 10

Deposition date:

2012-06-14

Original release date:

2012-11-02

Authors:

Qu, Hongchang; Ricklin, Daniel; Bai, Hongjun; Chen, Hui; Reis, Edimara; Maciejewski, Mateusz; Tzekou, Apostolia; DeAngelis, Robert; Resuello, Ranillo; Lupu, Florea; Barlow, Paul; Lambris, John

Citation:

Citation: Qu, Hongchang; Ricklin, Daniel; Bai, Hongjun; Chen, Hui; Reis, Edimara; Maciejewski, Mateusz; Tzekou, Apostolia; DeAngelis, Robert; Resuello, Ranillo; Lupu, Florea; Barlow, Paul; Lambris, John. "New analogs of the clinical complement inhibitor Compstatin with subnanomolar affinity and enhanced pharmacokinetic properties" Immunobiology 218, 496-505 (2013).
PubMed: 22795972

Assembly members:

Assembly members:
Compstatin_10, polymer, 15 residues, Formula weight is not available

Natural source:

Natural source: Common Name: not available Taxonomy ID: not available Superkingdom: not available Kingdom: not available Genus/species: not available not available

Experimental source:

Experimental source: Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Compstatin_10: XICVXQDWXAHRCIX

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
1H chemical shifts	102

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
Hide all

Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	Compstatin_10	1

Entities:

Entity 1, Compstatin_10 15 residues - Formula weight is not available

1

ACE

ILE

CYS

VAL

TRM

GLN

ASP

TRP

SAR

ALA

2

HIS

ARG

CYS

ILE

NH2

Samples:

sample_1: Compstatin 10 5 mM; Acetate, [U-100% 2H], 5 mM; H2O 90%; D2O 10%

sample_conditions_1: pH: 6.0; temperature: 288 K

Experiments:

Name	Sample	Sample state	Sample conditions
2D DQF-COSY	sample_1	isotropic	sample_conditions_1
2D 1H-1H TOCSY	sample_1	isotropic	sample_conditions_1
2D 1H-1H NOESY	sample_1	isotropic	sample_conditions_1

Software:

X-PLOR NIH v2.24, Schwieters, Kuszewski, Tjandra and Clore - structure solution

NMR spectrometers:

Bruker DRX 800 MHz
Bruker DRX 600 MHz