BMRB Entry 19476

Name: NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM Conus longurionis
Published: 2014-03-03

Click here to enlarge.

PDB ID: 2md6
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19476
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

Select model:

I am color blind

Download raw data. Direct link to this display. Help

Title:

NMR SOLUTION STRUCTURE OF ALPHA CONOTOXIN LO1A FROM Conus longurionis

Deposition date:

2013-09-01

Original release date:

2014-03-03

Authors:

Maiti, M.; Lescrinier, E.; Herdewijn, P.; Lebbe, E.; Peigneur, S.; D'Souza, L.; Tytgat, J.

Citation:

Citation: Lebbe, Eline; Peigneur, Steve; Maiti, Mohitosh; Devi, Prabha; Ravichandran, Samuthirapandian; Lescrinier, Eveline; Ulens, Chris; Waelkens, Etienne; Herdewijn, Lisette; Tytgat, Piet. "Structure-Function Elucidation of a New -Conotoxin, Lo1a, from Conus longurionis." J. Biol. Chem. 289, 9573-9583 (2014).
PubMed: 24567324

Assembly members:

Assembly members:
CONOTOXIN_LO1A, polymer, 18 residues, 1937.117 Da.

Natural source:

Natural source: Common Name: Conus longurionis Taxonomy ID: 1077918 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Conus longurionis

Experimental source:

Experimental source: Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
CONOTOXIN_LO1A: EGCCSNPACRTNHPEVCD

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
13C chemical shifts	48
1H chemical shifts	103

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
Hide all

Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	CONOTOXIN LO1A	1

Entities:

Entity 1, CONOTOXIN LO1A 18 residues - 1937.117 Da.

1

GLU

GLY

CYS

SER

ASN

PRO

ALA

CYS

ARG

2

THR

ASN

HIS

PRO

GLU

VAL

CYS

ASP

Samples:

sample: CONOTOXIN LO1A 2.6 mM

sample_conditions_1: pH: 5.9; pressure: 1 atm; temperature: 278 K

Experiments:

Name	Sample	Sample state	Sample conditions
2D DQF-COSY	sample	isotropic	sample_conditions_1
2D 1H-1H NOESY	sample	isotropic	sample_conditions_1
2D 1H-1H TOCSY	sample	isotropic	sample_conditions_1
2D 1H-13C HSQC aliphatic	sample	isotropic	sample_conditions_1
2D 1H-13C HSQC aromatic	sample	isotropic	sample_conditions_1

Software:

X-PLOR NIH v2.25, SCHWIETERS, KUSZEWSKI, TJ - refinement

TOPSPIN v2.1, Bruker - processing

NMR spectrometers:

BRUKER AVANCE 600 MHz

PDB	2MD6
SP	X1WB75
AlphaFold	X1WB75