BMRB Entry 18648

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PDB ID: 2lz4
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR18648
MolProbity Validation Chart

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Title:
APPTM V44M
Deposition date:
2012-08-07
Original release date:
2012-09-07
Authors:
Chen, Wen; Wang, Chunyu
Citation:

Citation: Chen, Wen; Gamache, Eric; Rosenman, David; Xie, Jian; Lopez, Maria; Li, Yue-Ming; Wang, Chunyu. "Familial Alzheimer's mutations within APPTM increase A42 production by enhancing accessibility of -cleavage site."  Nat. Commun. 5, 3037-3037 (2014).
PubMed: 24390130

Assembly members:

Assembly members:
V44M monomer, polymer, 32 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: PetM41

Entity Sequences (FASTA):

Entity Sequences (FASTA):
V44M monomer: GAMAKGAIIGLMVGGVVIAT MIVITLVMLKKK

Data sets:
Data typeCount
13C chemical shifts144
15N chemical shifts30
1H chemical shifts252

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
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Assembly:

Entity Assembly IDEntity NameEntity ID
1V44M chain, 11
2V44M chain, 21

Entities:

Entity 1, V44M chain, 1 32 residues - Formula weight is not available

1   GLYALAMETALALYSGLYALAILEILEGLY
2   LEUMETVALGLYGLYVALVALILEALATHR
3   METILEVALILETHRLEUVALMETLEULYS
4   LYSLYS

Related Database Links:

PDB 2LZ4

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