BMRB Entry 18596
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PDB ID: 2lvz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18596
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Garcia Mayoral, Maria Flor; Canales, Angeles; Diaz, Dolores; Lopez Prados, Javier; Moussaoui, Mohammed; de Paz, Jose Luis; Angulo, Jesus; Nieto, Pedro Manuel; Jimenez Barbero, Jesus; Boix, Ester; Bruix, Marta. "Insights into the glycosaminoglycan-mediated cytotoxic mechanism of eosinophil cationic protein revealed by NMR" ACS Chem. Biol. 8, 144-151 (2013).
PubMed: 23025322
Assembly members:
Eosinophil_Cationic_Protein, polymer, 133 residues, 15598.974 Da.
SUGAR_(3-MER), polymer, 3 residues, 595.473 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET11c
Entity Sequences (FASTA):
Eosinophil_Cationic_Protein: RPPQFTRAQWFAIQHISLNP
PRCTIAMRAINNYRWRCKNQ
NTFLRTTFANVVNVCGNQSI
RCPHNRTLNNCHRSRFRVPL
LHCDLINPGAQNISNCRYAD
RPGRRFYVVACDNRDPRDSP
RYPVVPVHLDTTI
SUGAR_(3-MER): XXX
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 410 |
| 15N chemical shifts | 148 |
| 1H chemical shifts | 923 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Eosinophil Cationic Protein | 1 |
| 2 | SUGAR (2-MER) | 2 |
Entities:
Entity 1, Eosinophil Cationic Protein 133 residues - 15598.974 Da.
| 1 | ARG | PRO | PRO | GLN | PHE | THR | ARG | ALA | GLN | TRP | ||||
| 2 | PHE | ALA | ILE | GLN | HIS | ILE | SER | LEU | ASN | PRO | ||||
| 3 | PRO | ARG | CYS | THR | ILE | ALA | MET | ARG | ALA | ILE | ||||
| 4 | ASN | ASN | TYR | ARG | TRP | ARG | CYS | LYS | ASN | GLN | ||||
| 5 | ASN | THR | PHE | LEU | ARG | THR | THR | PHE | ALA | ASN | ||||
| 6 | VAL | VAL | ASN | VAL | CYS | GLY | ASN | GLN | SER | ILE | ||||
| 7 | ARG | CYS | PRO | HIS | ASN | ARG | THR | LEU | ASN | ASN | ||||
| 8 | CYS | HIS | ARG | SER | ARG | PHE | ARG | VAL | PRO | LEU | ||||
| 9 | LEU | HIS | CYS | ASP | LEU | ILE | ASN | PRO | GLY | ALA | ||||
| 10 | GLN | ASN | ILE | SER | ASN | CYS | ARG | TYR | ALA | ASP | ||||
| 11 | ARG | PRO | GLY | ARG | ARG | PHE | TYR | VAL | VAL | ALA | ||||
| 12 | CYS | ASP | ASN | ARG | ASP | PRO | ARG | ASP | SER | PRO | ||||
| 13 | ARG | TYR | PRO | VAL | VAL | PRO | VAL | HIS | LEU | ASP | ||||
| 14 | THR | THR | ILE |
Entity 2, SUGAR (2-MER) 3 residues - 595.473 Da.
| 1 | LVZ | IDS | SGN |
Related Database Links:
| BMRB | 15757 |
| PDB | 1DYT 1H1H 1QMT 2KB5 2LVZ 4A2O 4A2Y 4OWZ 4OXB 4OXF |
| EMBL | CAA33251 CAA34545 CAA39462 |
| GB | AAA50283 AAC50143 AAC50150 AAG09050 AAG09051 |
| REF | NP_002926 XP_004054906 XP_004054907 |
| SP | P12724 P47778 P47780 |
| TPE | CDG31917 CDG31938 |
| AlphaFold | P12724 P47778 P47780 |
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