BMRB Entry 17731

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PDB ID: 2lew
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR17731
MolProbity Validation Chart

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Title:
Structural Plasticity of Paneth cell alpha-Defensins: Characterization of Salt-Bridge Deficient Analogues of Mouse Cryptdin-4
Deposition date:
2011-06-24
Original release date:
2012-05-09
Authors:
Rosengren, K. Johan; Andersson, Hakan; Haugaard-Kedstrom, Linda; Bengtsson, Elina; Daly, Norelle; Craik, David
Citation:

Citation: Andersson, Hakan; Figueredo, Sharel; Haugaard-Kedstrom, Linda; Bengtsson, Elina; Daly, Norelle; Qu, Xiaoqing; Craik, David; Ouellette, Andre; Rosengren, K. Johan. "The -defensin salt-bridge induces backbone stability to facilitate folding and confer proteolytic resistance."  Amino Acids 43, 1471-1483 (2012).
PubMed: 22286872

Assembly members:

Assembly members:
entity, polymer, 32 residues, 3699.551 Da.

Natural source:

Natural source:   Common Name: Mouse   Taxonomy ID: 10090   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Mus musculus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: GLLCYCRKGHCKRGGRVRGT CGIRFLYCCPRR

Data sets:
Data typeCount
1H chemical shifts205

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1(E15G)-Crp41

Entities:

Entity 1, (E15G)-Crp4 32 residues - 3699.551 Da.

1   GLYLEULEUCYSTYRCYSARGLYSGLYHIS
2   CYSLYSARGGLYGLYARGVALARGGLYTHR
3   CYSGLYILEARGPHELEUTYRCYSCYSPRO
4   ARGARG

Related Database Links:

PDB 2LEW