BMRB Entry 17364
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PDB ID: 2loz
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17364
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
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Citation: Chen, Lihong; Liu, Changdong; Ko, Frankie Chi Fat; Xu, Naining; Ng, Irene Oi-Lin; Yam, Judy Wai Ping; Zhu, Guang. "Solution structure of the phosphotyrosine binding (PTB) domain of human tensin2 protein in complex with deleted in liver cancer 1 (DLC1) peptide reveals a novel peptide binding mode." J. Biol. Chem. 287, 26104-26114 (2012).
PubMed: 22645138
Assembly members:
PTB_domian, polymer, 147 residues, 15983.273 Da.
DLC1_peptide, polymer, 21 residues, 2243.518 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: PET
Entity Sequences (FASTA):
PTB_domian: MSTAADLLRQGAACSVLYLT
SVETESLTGPQAVARASSAA
LSCSPRPTPAVVHFKVSAQG
ITLTDNQRKLFFRRHYPVNS
ITFSSTDPQDRRWTNPDGTT
SKIFGFVAKKPGSPWENVCH
LFAELDPDQPAGAIVTFITK
VLLGQRK
DLC1_peptide: IPEDHKPGTFPKALTNGSFS
P
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 484 |
| 15N chemical shifts | 133 |
| 1H chemical shifts | 992 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | PTB domian | 1 |
| 2 | DLC1 peptide | 2 |
Entities:
Entity 1, PTB domian 147 residues - 15983.273 Da.
| 1 | MET | SER | THR | ALA | ALA | ASP | LEU | LEU | ARG | GLN | ||||
| 2 | GLY | ALA | ALA | CYS | SER | VAL | LEU | TYR | LEU | THR | ||||
| 3 | SER | VAL | GLU | THR | GLU | SER | LEU | THR | GLY | PRO | ||||
| 4 | GLN | ALA | VAL | ALA | ARG | ALA | SER | SER | ALA | ALA | ||||
| 5 | LEU | SER | CYS | SER | PRO | ARG | PRO | THR | PRO | ALA | ||||
| 6 | VAL | VAL | HIS | PHE | LYS | VAL | SER | ALA | GLN | GLY | ||||
| 7 | ILE | THR | LEU | THR | ASP | ASN | GLN | ARG | LYS | LEU | ||||
| 8 | PHE | PHE | ARG | ARG | HIS | TYR | PRO | VAL | ASN | SER | ||||
| 9 | ILE | THR | PHE | SER | SER | THR | ASP | PRO | GLN | ASP | ||||
| 10 | ARG | ARG | TRP | THR | ASN | PRO | ASP | GLY | THR | THR | ||||
| 11 | SER | LYS | ILE | PHE | GLY | PHE | VAL | ALA | LYS | LYS | ||||
| 12 | PRO | GLY | SER | PRO | TRP | GLU | ASN | VAL | CYS | HIS | ||||
| 13 | LEU | PHE | ALA | GLU | LEU | ASP | PRO | ASP | GLN | PRO | ||||
| 14 | ALA | GLY | ALA | ILE | VAL | THR | PHE | ILE | THR | LYS | ||||
| 15 | VAL | LEU | LEU | GLY | GLN | ARG | LYS |
Entity 2, DLC1 peptide 21 residues - 2243.518 Da.
| 1 | ILE | PRO | GLU | ASP | HIS | LYS | PRO | GLY | THR | PHE | ||||
| 2 | PRO | LYS | ALA | LEU | THR | ASN | GLY | SER | PHE | SER | ||||
| 3 | PRO |
Related Database Links:
| BMRB | 10318 |
| PDB | 2DKQ 2LOZ 3HQC |
| DBJ | BAA83027 BAG09960 BAG54765 BAB21814 BAF82423 BAF84371 BAG10131 BAG61122 |
| EMBL | CAB70815 CAH56176 |
| GB | AAH54099 AAI10855 AAI29829 AAI29830 AAI31504 AAB81637 AAB87700 AAH54511 AAK97501 ACE86794 |
| REF | NP_056134 NP_736610 NP_938072 XP_001102202 XP_001790253 NP_001157743 NP_006085 NP_872584 XP_001092830 XP_003256738 |
| SP | Q63HR2 Q96QB1 |
| TPG | DAA29990 |
| PIR | G59435 |
| AlphaFold | Q63HR2 Q96QB1 |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks