BMRB Entry 16268

Title:
Human cannabinoid receptor-2 helix 6
Deposition date:
2009-04-28
Original release date:
2009-05-22
Authors:
Deshmukh, Lalit; Vinogradova, Olga; Tiburu, Elvis; Tyukhtenko, Sergiy; Janero, David; Makriyannis, Alexandros
Citation:

Citation: Tiburu, Elvis; Tyukhtenko, Sergiy; Deshmukh, Lalit; Vinogradova, Olga; Janero, David; Makriyannis, Alexandros. "Structural biology of human cannabinoid receptor-2 helix 6 in membranemimetic environments"  Biochem. Biophys. Res. Commun. 384, 243-248 (2009).
PubMed: 19397896

Assembly members:

Assembly members:
cannabinoid receptor-2 helix 6, polymer, 33 residues, 3553.421 Da.

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
cannabinoid receptor-2 helix 6: DVRLAKTLGLVLAVLLICWF PVLALMAHSLATT

Data sets:
Data typeCount
1H chemical shifts246

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1cannabinoid receptor-2 helix 61

Entities:

Entity 1, cannabinoid receptor-2 helix 6 33 residues - 3553.421 Da.

1   ASPVALARGLEUALALYSTHRLEUGLYLEU
2   VALLEUALAVALLEULEUILECYSTRPPHE
3   PROVALLEUALALEUMETALAHISSERLEU
4   ALATHRTHR

Samples:

sample_1: entity 1 mM; TFE 30%; H2O 95%; D2O 5%

sample_conditions_1: pressure: 1 atm; temperature: 300 K

sample_conditions_2: pressure: 1 atm; temperature: 310 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

CNS v1.2, Brunger, Adams, Clore, Gros, Nilges and Read - refinement

X-PLOR NIH v2.20, Schwieters, Kuszewski, Tjandra and Clore - structure solution

NMR spectrometers:

  • Bruker Avance 700 MHz

Related Database Links:

PDB
DBJ BAG72976
EMBL CAA52376 CAD22548 CAD22549 CAJ42137 CAJ42138
GB AAH69722 AAH74767 AAH95545 AAO92299 ACD31539
PRF 1920360A
REF NP_001832 XP_001105018 XP_001166334 XP_003271655 XP_004024947
SP P34972
AlphaFold P34972