BMRB Entry 15827

Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR15827

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Title:
Solution structure of antimicrobial peptide MSI-594, derived from Magainin-2 and Malittin, in the presence of LPS.
Deposition date:
2008-06-26
Original release date:
2009-06-15
Authors:
Bhunia, Anirban; Bhattacharjya, Surajit
Citation:

Citation: Bhunia, Anirban; Ramamoorthy, Ayyalusamy; Bhattacharjya, Surajit. "Helical hairpin structure of a potent antimicrobial peptide MSI-594 in lipopolysaccharide micelles by NMR spectroscopy"  Chemistry 15, 2036-2040 (2009).
PubMed: 19180607

Assembly members:

Assembly members:
MSI-594, polymer, 24 residues, 2447.125 Da.

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis   Host organism: solid phase peptide synthesis   Vector: Standard F-moc solid phase peptide synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
MSI-594: GIGKFLKKAKKGIGAVLKVL TTGL

Data sets:
Data typeCount
1H chemical shifts150

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1MSI-5941

Entities:

Entity 1, MSI-594 24 residues - 2447.125 Da.

1   GLYILEGLYLYSPHELEULYSLYSALALYS
2   LYSGLYILEGLYALAVALLEULYSVALLEU
3   THRTHRGLYLEU

Samples:

sample_1: MSI-594 0.5 mM

sample_conditions_1: pH: 4.5; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
2D 1H-1H transferred NOESYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1

Software:

DYANA v1.5, Guntert, Braun and Wuthrich - refinement

NMR spectrometers:

  • Bruker DRX 600 MHz

Related Database Links:

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