BMRB Entry 11559

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PDB ID: 2ruc
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR11559
MolProbity Validation Chart

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Title:
Solution structure of the peptidyl prolyl cis-trans isomerase domain of human Pin1 with sulfate ion
Deposition date:
2014-03-25
Original release date:
2014-12-15
Authors:
Xu, Ning; Tamari, Yu; Tochio, Naoya; Tate, Shin-ichi
Citation:

Citation: Xu, Ning; Tochio, Naoya; Wang, Jing; Tamari, Yu; Uewaki, Jun-ichi; Utsunomiya-Tate, Naoko; Igarashi, Kazuhiko; Shiraki, Takuma; Kobayashi, Naohiro; Tate, Shin-ichi. "The C113D mutation in human Pin1 causes allosteric structural changes in the phosphate binding pocket of the PPIase domain through the tug of war in the dual-histidine motif"  Biochemistry 53, 5568-5578 (2014).
PubMed: 25100325

Assembly members:

Assembly members:
wild_type_hPin1_PPIase_domain, polymer, 117 residues, 13121.837 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
wild_type_hPin1_PPIase_domain: GSHMEPARVRCSHLLVKHSQ SRRPSSWRQEKITRTKEEAL ELINGYIQKIKSGEEDFESL ASQFSDCSSAKARGDLGAFS RGQMQKPFEDASFALRTGEM SGPVFTDSGIHIILRTE

Data sets:
Data typeCount
13C chemical shifts507
15N chemical shifts127
1H chemical shifts804

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1wild type hPin1 PPIase domain1

Entities:

Entity 1, wild type hPin1 PPIase domain 117 residues - 13121.837 Da.

1   GLYSERHISMETGLUPROALAARGVALARG
2   CYSSERHISLEULEUVALLYSHISSERGLN
3   SERARGARGPROSERSERTRPARGGLNGLU
4   LYSILETHRARGTHRLYSGLUGLUALALEU
5   GLULEUILEASNGLYTYRILEGLNLYSILE
6   LYSSERGLYGLUGLUASPPHEGLUSERLEU
7   ALASERGLNPHESERASPCYSSERSERALA
8   LYSALAARGGLYASPLEUGLYALAPHESER
9   ARGGLYGLNMETGLNLYSPROPHEGLUASP
10   ALASERPHEALALEUARGTHRGLYGLUMET
11   SERGLYPROVALPHETHRASPSERGLYILE
12   HISILEILELEUARGTHRGLU

Related Database Links:

BMRB 11560
PDB 1F8A 1NMV 1NMW 1PIN 1ZCN 2F21 2ITK 2Q5A 2RUC 2RUD 2XP3 2XP4 2XP5 2XP6 2XP7 2XP8 2XP9 2XPA 2XPB 2ZQS 2ZQT 2ZQU 2ZQV 2ZR4 2ZR5 2ZR6 3KAB 3KAC 3KAD 3KAF 3KAG 3KAH 3KAI 3KCE 3NTP 3ODK 3OOB 3TC5 3TCZ 3TDB 3WH0 4QIB 4TNS 4U84 4U85 4U86
DBJ BAA87037 BAA87038 BAB22270 BAB22743 BAC35631
EMBL CAG28582
GB AAC50492 AAH02899 AAH38254 AAI12584 AAI58868
PRF 2209428A
REF NP_001029804 NP_001100171 NP_001231300 NP_001270625 NP_006212
SP Q13526 Q4R383 Q5BIN5 Q9QUR7
TPG DAA28013
AlphaFold Q13526 Q4R383 Q5BIN5 Q9QUR7

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks