BMRB Entry 6352

Title:
Isolation and characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis
Deposition date:
2004-10-14
Original release date:
2008-07-16
Authors:
Ekkelenkamp, Miquel; Hanssen, Micha; Hsu, Shang-Te; de Jong, Ad; Milatovic, Dana; Verhoef, Jan; van Nuland, Nico
Citation:

Citation: Ekkelenkamp, Miquel; Hanssen, Micha; Hsu, Shang-Te; de Jong, Ad; Milatovic, Dana; Verhoef, Jan; van Nuland, Nico. "Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis"  FEBS Lett. 579, 1917-1922 (2005).
PubMed: 15792796

Assembly members:

Assembly members:
Epilancin 15X, polymer, 31 residues, 3175.2 Da.

Natural source:

Natural source:   Common Name: Staphylococcus epidermidis   Taxonomy ID: 1282   Superkingdom: Eubacteria   Kingdom: not available   Genus/species: Staphylococcus epidermidis

Experimental source:

Experimental source:   Production method: purified from the natural source

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Epilancin 15X: XAXIVKXXIKAXKKLCRGFX LXCGCHFXGKK

Data sets:
Data typeCount
13C chemical shifts140
1H chemical shifts189

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Epilancin 15X1

Entities:

Entity 1, Epilancin 15X 31 residues - 3175.2 Da.

1   HOPALADHAILEVALLYSAA4AA4ILELYS
2   ALADALLYSLYSLEUCYSARGGLYPHEABA
3   LEUABACYSGLYCYSHISPHEAA4GLYLYS
4   LYS

Samples:

sample_water: Epilancin 15X 0.8 mM

sample_d2o: Epilancin 15X 3.1 mM

Ex-cond_1: pH: .; temperature: 305 K

Ex-cond_2: pH: .; temperature: 283 K

Experiments:

NameSampleSample stateSample conditions
1H-1H TOCSYnot availablenot availablenot available
1H-1H NOESYnot availablenot availablenot available
1H-13C HSQCnot availablenot availablenot available
1H-13C HMBCnot availablenot availablenot available

Software:

NMRPipe vn/a - data processing

NMRView v4.0.5 - Assignment

NMR spectrometers:

  • Bruker DRX 750 MHz

Related Database Links:

PDB