BMRB Entry 53359

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR53359

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
nGHR(413-432) Peptide
Deposition date:
2025-09-19
Original release date:
2026-08-22
Authors:
Sieme, Daniel; Kragelund, Birthe Brandt
Citation:

Citation: Kanis, Philipp; Berreiter, Miriam; Sieme, Daniel; Wootton, Olivia; Ju, Xiang-Chun; Holzwart, Nicholas; Hu, David Ziliang; Tadaka, Shu; Taira, Makiko; Kinoshita, Kengo; Agren, Richard; Olsen, Johan; Maricic, Tomislav; Martin, Hilary; Kragelund, Birthe; Paabo, Svante; Brooks, Andrew; Zeberg, Hugo. "Increased signaling of the Neanderthal growth hormone receptor "  Curr. Biol. 36, 4160-4172 (2026).
PubMed: 42556345

Assembly members:

Assembly members:
entity_1, polymer, 20 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: QNNSPYHDAFPATQQPSVIQ

Data sets:
Data typeCount
13C chemical shifts38
15N chemical shifts17
1H chemical shifts76

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1nGHR1

Entities:

Entity 1, nGHR 20 residues - Formula weight is not available

1   GLNASNASNSERPROTYRHISASPALAPHE
2   PROALATHRGLNGLNPROSERVALILEGLN

Samples:

sample_1: nGHR(413-432) 1.3 mM; D2O 5%; DSS 125 uM; sodium phosphate 20 mM; TCEP 1 mM

sample_conditions_1: ionic strength: 0 M; pH: 7.3; pressure: 1 atm; temperature: 283 K

Experiments:

NameSampleSample stateSample conditions
1D 1Hsample_1isotropicsample_conditions_1
2D 1H-15N HSQCsample_1isotropicsample_conditions_1
2D 1H-13C HSQCsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

POKY v20240829 - chemical shift assignment

NMR spectrometers:

  • Bruker AVANCE NEO 800 MHz

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks