BMRB Entry 2024

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR2024

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Title:
Sequential NMR Resonance Assignment and Structure Determination of the Kunitz-Type Inhibitor Domain of the Alzheimer's B-Amyloid Precursor Protein
Deposition date:
1995-07-31
Original release date:
1995-07-31
Authors:
Heald, S.; Tilton, Robert; Hammond, Lisa; Lee, Alice; Bayney, Richard; Kamarck, Michael; Ramabhadran, Triprayar; Dreyer, Robert; Davis, Gary; Unterbeck, Axel; Tamburini, Paul
Citation:

Citation: Heald, S.; Tilton, Robert; Hammond, Lisa; Lee, Alice; Bayney, Richard; Kamarck, Michael; Ramabhadran, Triprayar; Dreyer, Robert; Davis, Gary; Unterbeck, Axel; Tamburini, Paul. "Sequential NMR Resonance Assignment and Structure Determination of the Kunitz-Type Inhibitor Domain of the Alzheimer's B-Amyloid Precursor Protein"  Biochemistry 30, 10467-10478 (1991).

Assembly members:

Assembly members:
beta-amyloid precursor protein, polymer, 67 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: not available

Entity Sequences (FASTA):

Entity Sequences (FASTA):
beta-amyloid precursor protein: ANSMEVCSEQAETGPCRAMI SRWYFDVTEGKCAPFFYGGC GGNRNNFDTEEYCMAVCGSA KLGSGLD

Data sets:
Data typeCount
1H chemical shifts397

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1beta-amyloid precursor protein1

Entities:

Entity 1, beta-amyloid precursor protein 67 residues - Formula weight is not available

1   ALAASNSERMETGLUVALCYSSERGLUGLN
2   ALAGLUTHRGLYPROCYSARGALAMETILE
3   SERARGTRPTYRPHEASPVALTHRGLUGLY
4   LYSCYSALAPROPHEPHETYRGLYGLYCYS
5   GLYGLYASNARGASNASNPHEASPTHRGLU
6   GLUTYRCYSMETALAVALCYSGLYSERALA
7   LYSLEUGLYSERGLYLEUASP

Samples:

sample_one:

sample_condition_set_one: pH: 6.5 na; temperature: 298 K

Experiments:

NameSampleSample stateSample conditions
not availablesample_onenot availablesample_condition_set_one

Software:

No software information available

NMR spectrometers:

  • unknown unknown 0 MHz

Related Database Links:

PDB
DBJ BAA22264 BAA84580 BAD51938 BAE01907 BAE87853
EMBL CAA30042 CAA30050 CAA34116
GB AAA36828 AAA58727 AAB59501 AAB59502 AAD14347
PRF 1403400A
REF NP_000475 NP_001006601 NP_001013036 NP_001129488 NP_001129602
SP P05067 P08592 P29216 P53601 P79307
AlphaFold P53601 P08592 P05067 P29216 P79307