BMRB Entry 7008

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PDB ID: 2fwu
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR7008
MolProbity Validation Chart

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Title:
Second Ca2+ binding domain of the Na,Ca-exchanger (NCX1)
Deposition date:
2006-02-28
Original release date:
2006-04-11
Authors:
Hilge, M.; Vuister, G.; Aelen, J.
Citation:

Citation: Hilge, M.; Aelen, J.; Vuister, G.. "Ca(2+) regulation in the na(+)/ca(2+) exchanger involves two markedly different ca(2+) sensors"  Mol. Cell. 22, 15-25 (2006).
PubMed: 16600866

Assembly members:

Assembly members:
Sodium/calcium exchanger 1, polymer, 165 residues, Formula weight is not available
CA, non-polymer, 40.078 Da.

Natural source:

Natural source:   Common Name: Escherichia coli   Taxonomy ID: 562   Superkingdom: Bacteria   Kingdom: not available   Genus/species: Escherichia coli

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Sodium/calcium exchanger 1: MSHHHHHHHAGIFTFEEPVT HVSESIGIMEVKVLRTSGAR GNVIVPYKTIEGTARGGGED FEDTCGELEFQNDEIVKTIS VKVIDDEEYEKNKTFFLEIG EPRLVEMSEKKGGFTITEEY DDKQPLTSKEEEERRIAEMG RPILGEHTKLEVIIEESYEF KSTVD

Data sets:
Data typeCount
13C chemical shifts483
15N chemical shifts148
1H chemical shifts1044

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1Sodium/calcium exchanger 11
2CALCIUM (II) ION2

Entities:

Entity 1, Sodium/calcium exchanger 1 165 residues - Formula weight is not available

1   METSERHISHISHISHISHISHISHISALA
2   GLYILEPHETHRPHEGLUGLUPROVALTHR
3   HISVALSERGLUSERILEGLYILEMETGLU
4   VALLYSVALLEUARGTHRSERGLYALAARG
5   GLYASNVALILEVALPROTYRLYSTHRILE
6   GLUGLYTHRALAARGGLYGLYGLYGLUASP
7   PHEGLUASPTHRCYSGLYGLULEUGLUPHE
8   GLNASNASPGLUILEVALLYSTHRILESER
9   VALLYSVALILEASPASPGLUGLUTYRGLU
10   LYSASNLYSTHRPHEPHELEUGLUILEGLY
11   GLUPROARGLEUVALGLUMETSERGLULYS
12   LYSGLYGLYPHETHRILETHRGLUGLUTYR
13   ASPASPLYSGLNPROLEUTHRSERLYSGLU
14   GLUGLUGLUARGARGILEALAGLUMETGLY
15   ARGPROILELEUGLYGLUHISTHRLYSLEU
16   GLUVALILEILEGLUGLUSERTYRGLUPHE
17   LYSSERTHRVALASP

Entity 2, CALCIUM (II) ION - Ca - 40.078 Da.

1   CA

Related Database Links:

PDB 2FWU 2KLS
GB AAA19128 ELK14758

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