BMRB Entry 5945

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PDB ID: 1q69
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR5945
MolProbity Validation Chart

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Title:
A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8
Deposition date:
2003-09-11
Original release date:
2003-12-19
Authors:
Kim, Peter; Sun, Zhen-Yu; Blacklow, Stephen; Wagner, Gerhard; Eck, Michael
Citation:

Citation: Kim, Peter; Sun, Zhen-Yu; Blacklow, Stephen; Wagner, Gerhard; Eck, Michael. "A Zinc Clasp Structure Tethers Lck to T Cell Coreceptors CD4 and CD8"  Science (Washington, DC, U. S.) 301, 1725-1728 (2003).
PubMed: 14500983

Assembly members:

Assembly members:
CD8a, polymer, 19 residues, Formula weight is not available
Lck, polymer, 29 residues, Formula weight is not available
ZN, non-polymer, 65.409 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
CD8a: RNRRRVCKCPRPVVKSGDK
Lck: SHPEDDWLENIDVCENCHYP IVPLDGKGT

Data sets:
Data typeCount
1H chemical shifts268
13C chemical shifts148
15N chemical shifts41

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1CD8a cytoplasmic tail1
2Lck N-terminus2
3ZINC (II) ION3

Entities:

Entity 1, CD8a cytoplasmic tail 19 residues - Formula weight is not available

1   ARGASNARGARGARGVALCYSLYSCYSPRO
2   ARGPROVALVALLYSSERGLYASPLYS

Entity 2, Lck N-terminus 29 residues - Formula weight is not available

1   SERHISPROGLUASPASPTRPLEUGLUASN
2   ILEASPVALCYSGLUASNCYSHISTYRPRO
3   ILEVALPROLEUASPGLYLYSGLYTHR

Entity 3, ZINC (II) ION - Zn - 65.409 Da.

1   ZN

Related Database Links:

SWISS-PROT P01732
REF XP_001138871 XP_001138772 NP_741969 NP_001759
GenBank AAB04637 AAA79218 AAA79217 AAA61133 AAA59674
DBJ BAG61892 BAG53555
PDB 1Q69 1Q68
BMRB 5944

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