BMRB Entry 5173

Title:
NMR structure of human Epiregulin
Deposition date:
2001-10-01
Original release date:
2003-12-08
Authors:
Sato, Katsuharu; Miura, Kazunori; Tada, Masahito; Aizawa, Tomoyasu; Miyamoto, Kaoru; Kawano, Keiichi
Citation:

Citation: Sato, Katsuharu; Nakamura, T.; Mizuguchi, M.; Miura, Kazunori; Tada, Masahito; Aizawa, Tomoyasu; Gomi, T.; Miyamoto, Kaoru; Kawano, Keiichi. "Solution structure of epiregulin and the effect of its C-terminal domain for receptor binding affinity"  FEBS Lett. 553, 232-238 (2003).
PubMed: 14572630

Assembly members:

Assembly members:
Epiregulin, polymer, 46 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Epiregulin: VSITKCSSDMNGYCLHGQCI YLVDMSQNYCRCEVGYTGVR CEHFFL

Data sets:
Data typeCount
1H chemical shifts284

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1Epiregulin1

Entities:

Entity 1, Epiregulin 46 residues - Formula weight is not available

1   VALSERILETHRLYSCYSSERSERASPMET
2   ASNGLYTYRCYSLEUHISGLYGLNCYSILE
3   TYRLEUVALASPMETSERGLNASNTYRCYS
4   ARGCYSGLUVALGLYTYRTHRGLYVALARG
5   CYSGLUHISPHEPHELEU

Samples:

sample_1: Epiregulin 1.5 mM

cond_1: pH: 3.4; temperature: 303 K

Experiments:

NameSampleSample stateSample conditions

Software:

No software information available

NMR spectrometers:

  • Bruker DMX 500 MHz

Related Database Links:

PDB
DBJ BAA22146 BAG37463
EMBL CAG46685
GB AAI36405 AAI36406 AAX36706 AIC54356 EAX05709
REF NP_001423 XP_001155238 XP_002814919 XP_002919193 XP_003265794
SP O14944
AlphaFold O14944 O14944