BMRB Entry 34408

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PDB ID: 6rva
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR34408
MolProbity Validation Chart

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Title:
STRUCTURE OF [ASP58]-IGF-I ANALOGUE
Deposition date:
2019-05-31
Original release date:
2019-10-17
Authors:
Jiracek, J.; Zakova, L.; Socha, O.
Citation:

Citation: Machackova, K.; Mlcochova, K.; Potalitsyn, P.; Hankova, K.; Socha, O.; Budesinsky, M.; Muzdalo, A.; Lepsik, M.; Cernekova, M.; Radosavljevic, J.; Fabry, M.; Mitrova, K.; Chrudinova, M.; Lin, J.; Yurenko, Y.; Hobza, P.; Selicharova, I.; Akova, L.; Jiracek, J.. "Mutations at hypothetical binding site 2 in insulin and insulin-like growth factors 1 and 2 result in receptor- and hormone-specific responses."  J. Biol. Chem. 294, 17371-17382 (2019).
PubMed: 31558604

Assembly members:

Assembly members:
entity_1, polymer, 71 residues, 7706.778 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: GGPETLCGAELVDALQFVCG DRGFYFNKPTGYGSSSRRAP QTGIVDECCFRSCDLRRLDM YCAPLKPAKSA

Data sets:
Data typeCount
13C chemical shifts189
15N chemical shifts74
1H chemical shifts461

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 71 residues - 7706.778 Da.

1   GLYGLYPROGLUTHRLEUCYSGLYALAGLU
2   LEUVALASPALALEUGLNPHEVALCYSGLY
3   ASPARGGLYPHETYRPHEASNLYSPROTHR
4   GLYTYRGLYSERSERSERARGARGALAPRO
5   GLNTHRGLYILEVALASPGLUCYSCYSPHE
6   ARGSERCYSASPLEUARGARGLEUASPMET
7   TYRCYSALAPROLEULYSPROALALYSSER
8   ALA

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