BMRB Entry 34311

Title:
Solution structure of the RNA duplex formed by the 5'-end of U1snRNA and the 5'-splice site of SMN2 exon7
Deposition date:
2018-09-12
Original release date:
2019-08-07
Authors:
Campagne, S.; Allain, F.
Citation:

Citation: Campagne, Sebastien; Boigner, Sarah; Rudisser, Simon; Moursy, Ahmed; Gillioz, Laurent; Knorlein, Anna; Hall, Jonathan; Ratni, Hasane; Clery, Antoine; Allain, Frederic H-T. "Structural basis of a small molecule targeting RNA for a specific splicing correction"  Nat. Chem. Biol. 15, 1191-1198 (2019).
PubMed: 31636429

Assembly members:

Assembly members:
entity_1, polymer, 11 residues, 3428.074 Da.
entity_2, polymer, 11 residues, 3547.162 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: synthetic construct

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity_1: AUACXXACCUG
entity_2: GGAGUAAGUCU

Data sets:
Data typeCount
13C chemical shifts147
1H chemical shifts173

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11
2entity_22

Entities:

Entity 1, entity_1 11 residues - 3428.074 Da.

1   AUACPSUPSUACCU
2   G

Entity 2, entity_2 11 residues - 3547.162 Da.

1   GGAGUAAGUC
2   U