BMRB Entry 31038

Title:
NMR-derived ensemble of the TAZ2 domain of p300 bound to the microphthalmia-associated transcription factor
Deposition date:
2022-08-10
Original release date:
2023-06-15
Authors:
Langelaan, D.; Branch, M.
Citation:

Citation: Brown, A.; Vergunst, K.; Branch, M.; Blair, C.; Dupre, D.; Ballie, G.; Langelaan, D.. "Structural basis of CBP/p300 recruitment by the microphthalmia-associated transcription factor"  Biochim. Biophys. Acta Mol. Cell Res. 1870, 119520-119520 (2023).
PubMed: 37353163

Assembly members:

Assembly members:
entity_1, polymer, 34 residues, 3720.123 Da.
entity_2, polymer, 92 residues, 10107.916 Da.
entity_ZN, non-polymer, 65.409 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli

Data typeCount
13C chemical shifts512
15N chemical shifts131
1H chemical shifts792

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1unit_11
2unit_22
3unit_33
4unit_43
5unit_53

Entities:

Entity 1, unit_1 34 residues - 3720.123 Da.

1   GLYSERARGALASERCYSMETGLNMETASP
2   ASPVALILEASPASPILEILESERLEUGLU
3   SERSERTYRASNGLUGLUILELEUGLYLEU
4   METASPPROALA

Entity 2, unit_2 92 residues - 10107.916 Da.

1   GLYSERALATHRGLNSERPROGLYASPSER
2   ARGARGLEUSERILEGLNARGALAILEGLN
3   SERLEUVALHISALAALAGLNCYSARGASN
4   ALAASNCYSSERLEUPROSERCYSGLNLYS
5   METLYSARGVALVALGLNHISTHRLYSGLY
6   CYSLYSARGLYSTHRASNGLYGLYCYSPRO
7   ILECYSLYSGLNLEUILEALALEUALAALA
8   TYRHISALALYSHISCYSGLNGLUASNLYS
9   CYSPROVALPROPHECYSLEUASNILELYS
10   GLNLYS

Entity 3, unit_3 - Zn - 65.409 Da.

1   ZN

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