BMRB Entry 30324

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PDB ID: 5wow
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR30324
MolProbity Validation Chart

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Title:
Solution NMR structure of cyclotide MCoTI-I
Deposition date:
2017-08-03
Original release date:
2018-07-30
Authors:
Schroeder, C.; Kwon, S.
Citation:

Citation: Kwon, Soohyun; Duarte, Joao; Li, Zeyang; Ling, Jingjing; Cheneval, Olivier; Durek, Thomas; Schroeder, Christina; Craik, David; Ploegh, Hidde. "Targeted Delivery of Cyclotides via Conjugation to a Nanobody"  ACS Chem. Biol. 13, 2973-2980 (2018).
PubMed: 30248263

Assembly members:

Assembly members:
Two inhibitor peptide topologies 2, polymer, 39 residues, 4247.842 Da.

Natural source:

Natural source:   Common Name: Spiny bitter cucumber   Taxonomy ID: 3674   Superkingdom: Eukaryota   Kingdom: Viridiplantae   Genus/species: Momordica cochinchinensis

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Two inhibitor peptide topologies 2: GGVCPKILQRCRRDSDCPGA CICRGNGYCGYPYDVPDYA

Data sets:
Data typeCount
13C chemical shifts105
15N chemical shifts40
1H chemical shifts236

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Assembly:

Entity Assembly IDEntity NameEntity ID
1entity_11

Entities:

Entity 1, entity_1 39 residues - 4247.842 Da.

1   GLYGLYVALCYSPROLYSILELEUGLNARG
2   CYSARGARGASPSERASPCYSPROGLYALA
3   CYSILECYSARGGLYASNGLYTYRCYSGLY
4   TYRPROTYRASPVALPROASPTYRALA

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