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PDB ID: 5j18
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR30048
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Athuluri-Divakar, S.; Vasquez-Del Carpio, R.; Dutta, K.; Baker, S.; Cosenza, S.; Basu, I.; Gupta, Y.; Reddy, M.; Ueno, L.; Hart, J.; Vogt, P.; Mulholland, D.; Guha, C.; Aggarwal, A.; Reddy, E.. "A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling" Cell 165, 643-655 (2016).
PubMed: 27104980
Assembly members:
entity_1, polymer, 92 residues, 10311.078 Da.
entity_6FS, non-polymer, 451.490 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli
Entity Sequences (FASTA):
entity_1: GSLEVLFQGPSPQKPIVRVF
LPNKQRTVVPARCGVTVRDS
LKKALMMRGLIPECCAVYRI
QDGEKKPIGWDTDISWLTGE
ELHVEVLENVPL
Data type | Count |
13C chemical shifts | 378 |
15N chemical shifts | 76 |
1H chemical shifts | 603 |
Entity Assembly ID | Entity Name | Entity ID |
---|---|---|
1 | entity_1 | 1 |
2 | entity_2 | 2 |
Entity 1, entity_1 92 residues - 10311.078 Da.
1 | GLY | SER | LEU | GLU | VAL | LEU | PHE | GLN | GLY | PRO | ||||
2 | SER | PRO | GLN | LYS | PRO | ILE | VAL | ARG | VAL | PHE | ||||
3 | LEU | PRO | ASN | LYS | GLN | ARG | THR | VAL | VAL | PRO | ||||
4 | ALA | ARG | CYS | GLY | VAL | THR | VAL | ARG | ASP | SER | ||||
5 | LEU | LYS | LYS | ALA | LEU | MET | MET | ARG | GLY | LEU | ||||
6 | ILE | PRO | GLU | CYS | CYS | ALA | VAL | TYR | ARG | ILE | ||||
7 | GLN | ASP | GLY | GLU | LYS | LYS | PRO | ILE | GLY | TRP | ||||
8 | ASP | THR | ASP | ILE | SER | TRP | LEU | THR | GLY | GLU | ||||
9 | GLU | LEU | HIS | VAL | GLU | VAL | LEU | GLU | ASN | VAL | ||||
10 | PRO | LEU |
Entity 2, entity_2 - C21 H25 N O8 S - 451.490 Da.
1 | 6FS |
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