BMRB Entry 27598

Name: XRCC1-BRCT1
Published: 2019-02-07

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR27598

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Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

XRCC1-BRCT1

Deposition date:

2018-09-05

Original release date:

2019-02-07

Authors:

Polo, Luis; Xu, Yingqi; Matthews, Steve; Oliver, Antony; Pearl, Laurence

Citation:

Citation: Polo, Luis; Xu, Yingqi; Hornyak, Peter; Garces, Fernando; Zeng, Zhihong; Hailstone, Richard; Matthews, Steve; Caldecott, Keith; Oliver, Antony; Pearl, Laurence. "Efficient Single-Strand Break Repair Requires Binding to Both Poly(ADP-Ribose) and DNA by the Central BRCT Domain of XRCC1." Cell Rep. 26, 573-581 (2019).
PubMed: 30650352

Assembly members:

Assembly members:
XRCC1-BRCT1, polymer, 110 residues, Formula weight is not available

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET15b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
XRCC1-BRCT1: GEGTEPRRPRAGPEELGKIL QGVVVVLSGFQNPFRSELRD KALELGAKYRPDWTRDSTHL ICAFANTPKYSQVLGLGGRI VRKEWVLDCHRMRRRLPSRR YLMAGPGSSS

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
13C chemical shifts	276
15N chemical shifts	87
1H chemical shifts	87

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	XRCC1-BRCT1	1

Entities:

Entity 1, XRCC1-BRCT1 110 residues - Formula weight is not available

1	GLY	GLU	GLY	THR	GLU	PRO	ARG	ARG	PRO	ARG
2	ALA	GLY	PRO	GLU	GLU	LEU	GLY	LYS	ILE	LEU
3	GLN	GLY	VAL	VAL	VAL	VAL	LEU	SER	GLY	PHE
4	GLN	ASN	PRO	PHE	ARG	SER	GLU	LEU	ARG	ASP
5	LYS	ALA	LEU	GLU	LEU	GLY	ALA	LYS	TYR	ARG
6	PRO	ASP	TRP	THR	ARG	ASP	SER	THR	HIS	LEU
7	ILE	CYS	ALA	PHE	ALA	ASN	THR	PRO	LYS	TYR
8	SER	GLN	VAL	LEU	GLY	LEU	GLY	GLY	ARG	ILE
9	VAL	ARG	LYS	GLU	TRP	VAL	LEU	ASP	CYS	HIS
10	ARG	MET	ARG	ARG	ARG	LEU	PRO	SER	ARG	ARG
11	TYR	LEU	MET	ALA	GLY	PRO	GLY	SER	SER	SER

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
3D CBCA(CO)NH	sample_1	isotropic	sample_conditions_1
3D C(CO)NH	sample_1	isotropic	sample_conditions_1

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks

BMRB Entry 27598

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers:

1	GLY	GLU	GLY	THR	GLU	PRO	ARG	ARG	PRO	ARG
2	ALA	GLY	PRO	GLU	GLU	LEU	GLY	LYS	ILE	LEU
3	GLN	GLY	VAL	VAL	VAL	VAL	LEU	SER	GLY	PHE
4	GLN	ASN	PRO	PHE	ARG	SER	GLU	LEU	ARG	ASP
5	LYS	ALA	LEU	GLU	LEU	GLY	ALA	LYS	TYR	ARG
6	PRO	ASP	TRP	THR	ARG	ASP	SER	THR	HIS	LEU
7	ILE	CYS	ALA	PHE	ALA	ASN	THR	PRO	LYS	TYR
8	SER	GLN	VAL	LEU	GLY	LEU	GLY	GLY	ARG	ILE
9	VAL	ARG	LYS	GLU	TRP	VAL	LEU	ASP	CYS	HIS
10	ARG	MET	ARG	ARG	ARG	LEU	PRO	SER	ARG	ARG
11	TYR	LEU	MET	ALA	GLY	PRO	GLY	SER	SER	SER

1	GLY	GLU	GLY	THR	GLU	PRO	ARG	ARG	PRO	ARG
2	ALA	GLY	PRO	GLU	GLU	LEU	GLY	LYS	ILE	LEU
3	GLN	GLY	VAL	VAL	VAL	VAL	LEU	SER	GLY	PHE
4	GLN	ASN	PRO	PHE	ARG	SER	GLU	LEU	ARG	ASP
5	LYS	ALA	LEU	GLU	LEU	GLY	ALA	LYS	TYR	ARG
6	PRO	ASP	TRP	THR	ARG	ASP	SER	THR	HIS	LEU
7	ILE	CYS	ALA	PHE	ALA	ASN	THR	PRO	LYS	TYR
8	SER	GLN	VAL	LEU	GLY	LEU	GLY	GLY	ARG	ILE
9	VAL	ARG	LYS	GLU	TRP	VAL	LEU	ASP	CYS	HIS
10	ARG	MET	ARG	ARG	ARG	LEU	PRO	SER	ARG	ARG
11	TYR	LEU	MET	ALA	GLY	PRO	GLY	SER	SER	SER

1	GLY	GLU	GLY	THR	GLU	PRO	ARG	ARG	PRO	ARG
2	ALA	GLY	PRO	GLU	GLU	LEU	GLY	LYS	ILE	LEU
3	GLN	GLY	VAL	VAL	VAL	VAL	LEU	SER	GLY	PHE
4	GLN	ASN	PRO	PHE	ARG	SER	GLU	LEU	ARG	ASP
5	LYS	ALA	LEU	GLU	LEU	GLY	ALA	LYS	TYR	ARG
6	PRO	ASP	TRP	THR	ARG	ASP	SER	THR	HIS	LEU
7	ILE	CYS	ALA	PHE	ALA	ASN	THR	PRO	LYS	TYR
8	SER	GLN	VAL	LEU	GLY	LEU	GLY	GLY	ARG	ILE
9	VAL	ARG	LYS	GLU	TRP	VAL	LEU	ASP	CYS	HIS
10	ARG	MET	ARG	ARG	ARG	LEU	PRO	SER	ARG	ARG
11	TYR	LEU	MET	ALA	GLY	PRO	GLY	SER	SER	SER