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PDB ID: 6hkc
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR27581
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Rice, Heather; de Malmazet, Daniel; Schreurs, An; Frere, Samuel; Van Molle, Inge; Volkov, Alexander; Creemers, Eline; Vertkin, Irena; Nys, Julie; Ranaivoson, Fanomezana; Comoletti, Davide; Savas, Jeffrey; Remaut, Han; Balschun, Detlef; Wierda, Keimpe; Slutsky, Inna; Farrow, Karl; De Strooper, Bart; de Wit, Joris. "Secreted amyloid-beta precursor protein functions as a GABA" Science 363, 4827-4827 (2019).
PubMed: 30630900
Assembly members:
Sushi1, polymer, 75 residues, Formula weight is not available
APPP, polymer, 9 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET24-6 His-SUMO
Entity Sequences (FASTA):
Sushi1: GPTSEGCQIIHPPWEGGIRY
RGLTRDQVKAINFLPVDYEI
EYVCRGEREVVGPKVRKCLA
NGSWTDMDTPSRCVR
APPP: DDSDVWWGG
Data type | Count |
13C chemical shifts | 326 |
15N chemical shifts | 73 |
1H chemical shifts | 515 |
Entity Assembly ID | Entity Name | Entity ID |
---|---|---|
1 | Sushi1 | 1 |
2 | APPP | 2 |
Entity 1, Sushi1 75 residues - Formula weight is not available
1 | GLY | PRO | THR | SER | GLU | GLY | CYS | GLN | ILE | ILE | ||||
2 | HIS | PRO | PRO | TRP | GLU | GLY | GLY | ILE | ARG | TYR | ||||
3 | ARG | GLY | LEU | THR | ARG | ASP | GLN | VAL | LYS | ALA | ||||
4 | ILE | ASN | PHE | LEU | PRO | VAL | ASP | TYR | GLU | ILE | ||||
5 | GLU | TYR | VAL | CYS | ARG | GLY | GLU | ARG | GLU | VAL | ||||
6 | VAL | GLY | PRO | LYS | VAL | ARG | LYS | CYS | LEU | ALA | ||||
7 | ASN | GLY | SER | TRP | THR | ASP | MET | ASP | THR | PRO | ||||
8 | SER | ARG | CYS | VAL | ARG |
Entity 2, APPP 9 residues - Formula weight is not available
1 | ASP | ASP | SER | ASP | VAL | TRP | TRP | GLY | GLY |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
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SPARKY: Backbone
or all simulated peaks