BMRB Entry 27575

Chem Shift validation: AVS_full
BMRB Entry DOI: doi:10.13018/BMR27575

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Title:
Backbone 1H, 13C, and 15N Chemical Shift Assignments for transthyetin in 5% DMSO
Deposition date:
2018-08-13
Original release date:
2018-09-12
Authors:
Yu, Tsyr-Yan; Yen, Yueh-Jung; Chang, Yu; Huang, Shing-Jong
Citation:

Citation: Liu, Yo-Tsen; Yen, Yueh-Jung; Ricardo, Frans; Chang, Yu; Wu, Pei-Hao; Huang, Shing-Jong; Lin, Kon-Ping; Yu, Tsyr-Yan. "Biophysical characterization and modulation of Transthyretin Ala97Ser"  Ann. Clin. Transl. Neurol. 6, 1961-1970 (2019).
PubMed: 31502419

Assembly members:

Assembly members:
wtTTR, polymer, 127 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET21b

Entity Sequences (FASTA):

Entity Sequences (FASTA):
wtTTR: GPTGTGESKCPLMVKVLDAV RGSPAINVAVHVFRKAADDT WEPFASGKTSESGELHGLTT EEEFVEGIYKVEIDTKSYWK ALGISPFHEHAEVVFTANDS GPRRYTIAALLSPYSYSTTA VVTNPKE

Data sets:
Data typeCount
13C chemical shifts125
15N chemical shifts116
1H chemical shifts116

Additional metadata:

  • Assembly
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Assembly:

Entity Assembly IDEntity NameEntity ID
1wtTTR1

Entities:

Entity 1, wtTTR 127 residues - Formula weight is not available

1   GLYPROTHRGLYTHRGLYGLUSERLYSCYS
2   PROLEUMETVALLYSVALLEUASPALAVAL
3   ARGGLYSERPROALAILEASNVALALAVAL
4   HISVALPHEARGLYSALAALAASPASPTHR
5   TRPGLUPROPHEALASERGLYLYSTHRSER
6   GLUSERGLYGLULEUHISGLYLEUTHRTHR
7   GLUGLUGLUPHEVALGLUGLYILETYRLYS
8   VALGLUILEASPTHRLYSSERTYRTRPLYS
9   ALALEUGLYILESERPROPHEHISGLUHIS
10   ALAGLUVALVALPHETHRALAASNASPSER
11   GLYPROARGARGTYRTHRILEALAALALEU
12   LEUSERPROTYRSERTYRSERTHRTHRALA
13   VALVALTHRASNPROLYSGLU

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks