BMRB Entry 26977
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR26977
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NMR-STAR v3 text file.
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Citation: Natarajan, Kannan; McShan, Andrew; Jiang, Jiansheng; Kumirov, Vlad; Wang, Rui; Zhao, Huaying; Schuck, Peter; Tilahun, Mulualem; Boyd, Lisa; Ying, Jinfa; Bax, Ad; Margulies, David; Sgourakis, Nikolaos. "An allosteric site in the T-cell receptor Cbeta domain plays a critical signalling role" Nat. Commun. 8, 15260-15260 (2017).
PubMed: 28508865
Assembly members:
B4.2.3_T-cell_receptor_Beta-chain, polymer, 236 residues, Formula weight is not available
B4.2.3_T-cell_receptor_Alpha-chain, polymer, 204 residues, Formula weight is not available
Natural source: Common Name: Mouse Taxonomy ID: 10090 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Mus musculus
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET21a
Entity Sequences (FASTA):
B4.2.3_T-cell_receptor_Beta-chain: MKVTQMPRYLIKRMGENVLL
ECGQDMSHETMYWYRQDPGL
GLQLIYISYDVDSNSEGDIP
KGYRVSRKKREHFSLILDSA
KTNQTSVYFCASSLGHTEVF
FGKGTRLTVVEDLRNVTPPK
VSLFEPSKAEIANKQKATLV
CLARGFFPDHVELSWWVNGK
EVHSGVCTDPQAYKESNYSY
ALSSRLRVSATFWHNPRNHF
RCQVQFHGLSEEDKWPEGSP
KPVTQNISAEAWGRAD
B4.2.3_T-cell_receptor_Alpha-chain: MQQVRQSPQSLTVWEGETAI
LNCSYENSAFDYFPWYQQFP
GEGPALLISILSVSNKKEDG
RFTIFFNKREKKLSLHIADS
QPGDSATYFCAASASFGDNS
KLIWGLGTSLVVNPNIQNPE
PAVYQLKDPRSQDSTLCLFT
DFDSQINVPKTMEPGTFITD
KCVLDMKAMDSKSNGAIAWS
NQTSFTCQDIFKETNATYPS
SDVP
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 698 |
| 15N chemical shifts | 197 |
| 1H chemical shifts | 470 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | Beta-chain | 1 |
| 2 | Alpha-chain | 2 |
Entities:
Entity 1, Beta-chain 236 residues - Formula weight is not available
Ecotodomain of B4.2.3 T-cell receptor Beta-chain
| 1 | MET | LYS | VAL | THR | GLN | MET | PRO | ARG | TYR | LEU | ||||
| 2 | ILE | LYS | ARG | MET | GLY | GLU | ASN | VAL | LEU | LEU | ||||
| 3 | GLU | CYS | GLY | GLN | ASP | MET | SER | HIS | GLU | THR | ||||
| 4 | MET | TYR | TRP | TYR | ARG | GLN | ASP | PRO | GLY | LEU | ||||
| 5 | GLY | LEU | GLN | LEU | ILE | TYR | ILE | SER | TYR | ASP | ||||
| 6 | VAL | ASP | SER | ASN | SER | GLU | GLY | ASP | ILE | PRO | ||||
| 7 | LYS | GLY | TYR | ARG | VAL | SER | ARG | LYS | LYS | ARG | ||||
| 8 | GLU | HIS | PHE | SER | LEU | ILE | LEU | ASP | SER | ALA | ||||
| 9 | LYS | THR | ASN | GLN | THR | SER | VAL | TYR | PHE | CYS | ||||
| 10 | ALA | SER | SER | LEU | GLY | HIS | THR | GLU | VAL | PHE | ||||
| 11 | PHE | GLY | LYS | GLY | THR | ARG | LEU | THR | VAL | VAL | ||||
| 12 | GLU | ASP | LEU | ARG | ASN | VAL | THR | PRO | PRO | LYS | ||||
| 13 | VAL | SER | LEU | PHE | GLU | PRO | SER | LYS | ALA | GLU | ||||
| 14 | ILE | ALA | ASN | LYS | GLN | LYS | ALA | THR | LEU | VAL | ||||
| 15 | CYS | LEU | ALA | ARG | GLY | PHE | PHE | PRO | ASP | HIS | ||||
| 16 | VAL | GLU | LEU | SER | TRP | TRP | VAL | ASN | GLY | LYS | ||||
| 17 | GLU | VAL | HIS | SER | GLY | VAL | CYS | THR | ASP | PRO | ||||
| 18 | GLN | ALA | TYR | LYS | GLU | SER | ASN | TYR | SER | TYR | ||||
| 19 | ALA | LEU | SER | SER | ARG | LEU | ARG | VAL | SER | ALA | ||||
| 20 | THR | PHE | TRP | HIS | ASN | PRO | ARG | ASN | HIS | PHE | ||||
| 21 | ARG | CYS | GLN | VAL | GLN | PHE | HIS | GLY | LEU | SER | ||||
| 22 | GLU | GLU | ASP | LYS | TRP | PRO | GLU | GLY | SER | PRO | ||||
| 23 | LYS | PRO | VAL | THR | GLN | ASN | ILE | SER | ALA | GLU | ||||
| 24 | ALA | TRP | GLY | ARG | ALA | ASP |
Entity 2, Alpha-chain 204 residues - Formula weight is not available
| 1 | MET | GLN | GLN | VAL | ARG | GLN | SER | PRO | GLN | SER | ||||
| 2 | LEU | THR | VAL | TRP | GLU | GLY | GLU | THR | ALA | ILE | ||||
| 3 | LEU | ASN | CYS | SER | TYR | GLU | ASN | SER | ALA | PHE | ||||
| 4 | ASP | TYR | PHE | PRO | TRP | TYR | GLN | GLN | PHE | PRO | ||||
| 5 | GLY | GLU | GLY | PRO | ALA | LEU | LEU | ILE | SER | ILE | ||||
| 6 | LEU | SER | VAL | SER | ASN | LYS | LYS | GLU | ASP | GLY | ||||
| 7 | ARG | PHE | THR | ILE | PHE | PHE | ASN | LYS | ARG | GLU | ||||
| 8 | LYS | LYS | LEU | SER | LEU | HIS | ILE | ALA | ASP | SER | ||||
| 9 | GLN | PRO | GLY | ASP | SER | ALA | THR | TYR | PHE | CYS | ||||
| 10 | ALA | ALA | SER | ALA | SER | PHE | GLY | ASP | ASN | SER | ||||
| 11 | LYS | LEU | ILE | TRP | GLY | LEU | GLY | THR | SER | LEU | ||||
| 12 | VAL | VAL | ASN | PRO | ASN | ILE | GLN | ASN | PRO | GLU | ||||
| 13 | PRO | ALA | VAL | TYR | GLN | LEU | LYS | ASP | PRO | ARG | ||||
| 14 | SER | GLN | ASP | SER | THR | LEU | CYS | LEU | PHE | THR | ||||
| 15 | ASP | PHE | ASP | SER | GLN | ILE | ASN | VAL | PRO | LYS | ||||
| 16 | THR | MET | GLU | PRO | GLY | THR | PHE | ILE | THR | ASP | ||||
| 17 | LYS | CYS | VAL | LEU | ASP | MET | LYS | ALA | MET | ASP | ||||
| 18 | SER | LYS | SER | ASN | GLY | ALA | ILE | ALA | TRP | SER | ||||
| 19 | ASN | GLN | THR | SER | PHE | THR | CYS | GLN | ASP | ILE | ||||
| 20 | PHE | LYS | GLU | THR | ASN | ALA | THR | TYR | PRO | SER | ||||
| 21 | SER | ASP | VAL | PRO |
Download HSQC peak lists in one of the following formats:
CSV: Backbone
or all simulated peaks
SPARKY: Backbone
or all simulated peaks