BMRB Entry 26943
Chem Shift validation: AVS_anomalous, AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR26943
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Citation: Kim, Sun-Kyung; Myers, Lindsey; Hinck, Cynthia; Can, Kristin; Thirangala, Avi; Iskra, Brian; Brothers, Molly; Vonberg, Machell; Leal, Belinda; Richter, Blair; Kodak, Ravindra; Taylor, Alex; Du, Shoucheng; Barnes, Christopher; Calero, Guillermo; Hart, Peter; Hart, Matthew; Demeler, Borries; Hinck, Andrew. "An engineered TGF-beta monomer that functions as a dominant negative to block TGF-beta signaling" J. Biol. Chem. 292, 7173-7188 (2017).
PubMed: 28228478
Assembly members:
mmTGF-b2, polymer, 93 residues, Formula weight is not available
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET32a
Entity Sequences (FASTA):
mmTGF-b2: MALDAAYCFRNVQDNCCLRP
LYIDFKRDCGWKWIHEPKGY
NANFCAGACPYRNSKSPSCV
SQDLEPLTILYYIGKTPKIE
QLSNMIVKSCKCS
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 272 |
| 15N chemical shifts | 86 |
| 1H chemical shifts | 86 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | mmTGF-b2 | 1 |
Entities:
Entity 1, mmTGF-b2 93 residues - Formula weight is not available
| 1 | MET | ALA | LEU | ASP | ALA | ALA | TYR | CYS | PHE | ARG | ||||
| 2 | ASN | VAL | GLN | ASP | ASN | CYS | CYS | LEU | ARG | PRO | ||||
| 3 | LEU | TYR | ILE | ASP | PHE | LYS | ARG | ASP | CYS | GLY | ||||
| 4 | TRP | LYS | TRP | ILE | HIS | GLU | PRO | LYS | GLY | TYR | ||||
| 5 | ASN | ALA | ASN | PHE | CYS | ALA | GLY | ALA | CYS | PRO | ||||
| 6 | TYR | ARG | ASN | SER | LYS | SER | PRO | SER | CYS | VAL | ||||
| 7 | SER | GLN | ASP | LEU | GLU | PRO | LEU | THR | ILE | LEU | ||||
| 8 | TYR | TYR | ILE | GLY | LYS | THR | PRO | LYS | ILE | GLU | ||||
| 9 | GLN | LEU | SER | ASN | MET | ILE | VAL | LYS | SER | CYS | ||||
| 10 | LYS | CYS | SER |
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