BMRB Entry 19979

Title:
Solution structure of B24G insulin
Deposition date:
2014-05-19
Original release date:
2014-12-22
Authors:
Yang, Yanwu; Wickramasinghe, Nalinda; Hua, Qingxin; Weiss, Michael
Citation:

Citation: Menting, John; Yang, Yanwu; Chan, Shu; Phillips, Nelson; Smith, Brian; Whittaker, Jonathan; Wickramasinghe, Nalinda; Whittaker, Linda; Pandyarajan, Vijay; Wan, Zhu-li; Yadav, Satya; Carroll, Julie; Strokes, Natalie; Roberts, Charles; Ismail-Beigi, Faramarz; Milewski, Wieslawa; Steiner, Donald; Chauhan, Virander; Ward, Colin; Weiss, Michael; Lawrence, Michael. "Protective hinge in insulin opens to enable its receptor engagement"  Proc. Natl. Acad. Sci. U.S.A. 111, E3395-E3404 (2014).
PubMed: 25092300

Assembly members:

Assembly members:
entity, polymer, 51 residues, 5686.482 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Data sets:
Data typeCount
1H chemical shifts261

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1B24G insulin1

Entities:

Entity 1, B24G insulin 51 residues - 5686.482 Da.

1   GLYILEVALGLUGLNCYSCYSTHRSERILE
2   CYSSERLEUTYRGLNLEUGLUASNTYRCYS
3   ASNPHEVALASNGLNHISLEUCYSGLYSER
4   ASPLEUVALGLUALALEUTYRLEUVALCYS
5   GLYGLUARGGLYGLYPHETYRTHRLYSPRO
6   THR