BMRB Entry 19787

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR19787

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Title:
Human FKBP51-FK506 binding domain 1
Deposition date:
2014-02-11
Original release date:
2014-08-06
Authors:
Mustafi, Sourajit; LeMaster, David; Hernandez, Griselda
Citation:

Citation: Mustafi, Sourajit; LeMaster, David; Hernandez, Griselda. "Differential Conformational Dynamics in the Closely Homologous FK506-binding Domains of FKBP51 and FKBP52"  Biochem J. 461, 115-123 (2014).
PubMed: 24749623

Assembly members:

Assembly members:
FKBP51, polymer, 122 residues, 13537.59 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET11a

Entity Sequences (FASTA):

Entity Sequences (FASTA):
FKBP51: MEQGEDITSKKDRGVLKIVK RVGNGEETPMIGDKVYVHYK GKLSNGKKFDSSHDRNEPFV FSLGKGQVIKAWDIGVATMK KGEICHLLCKPEYAYGSAGS LPKIPSNATLFFEIELLDFK GE

Data sets:
Data typeCount
13C chemical shifts351
15N chemical shifts114
1H chemical shifts250

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1FKBP511

Entities:

Entity 1, FKBP51 122 residues - 13537.59 Da.

1   METGLUGLNGLYGLUASPILETHRSERLYS
2   LYSASPARGGLYVALLEULYSILEVALLYS
3   ARGVALGLYASNGLYGLUGLUTHRPROMET
4   ILEGLYASPLYSVALTYRVALHISTYRLYS
5   GLYLYSLEUSERASNGLYLYSLYSPHEASP
6   SERSERHISASPARGASNGLUPROPHEVAL
7   PHESERLEUGLYLYSGLYGLNVALILELYS
8   ALATRPASPILEGLYVALALATHRMETLYS
9   LYSGLYGLUILECYSHISLEULEUCYSLYS
10   PROGLUTYRALATYRGLYSERALAGLYSER
11   LEUPROLYSILEPROSERASNALATHRLEU
12   PHEPHEGLUILEGLULEULEUASPPHELYS
13   GLYGLU

Related Database Links:

PDB 3O5P 3O5E 3O5F 3O5G 3O5I 3O5J 3O5K 3O5L 3O5M 3O5O 3O5Q 3O5R 4DRH 4DRI 4DRK 4DRM 4DRN 4DRO 4DRP 4DRQ 4JFI 4JFJ 4JFK 4JFL 4JFM 4R0X 4TW6 4TW7 4TX0 4W9O 4W9P 4W9Q 5DIT
DBJ BAD93130
GB AAI18470
REF NP_001139249 XP_003897552 XP_012387759 XP_013833287 XP_013833288

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks