BMRB Entry 19654
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PDB ID: 2mhs
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19654
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry
Citation: Liu, Gaohua; Poppe, Leszek; Aoki, Ken; Yamane, Harvey; Lewis, Jeffrey; Szyperski, Thomas. "High-quality NMR Structure of Human Anti-apoptotic Protein Domain Mcl-1(171-327) for Cancer Drug Design" PLOS 9, e96521-e96521 (2014).
PubMed: 24789074
Assembly members:
entity, polymer, 328 residues, 37715.047 Da.
Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pSR482-21.1
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 548 |
| 15N chemical shifts | 175 |
| 1H chemical shifts | 1153 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | human Mcl-1 | 1 |
Entities:
Entity 1, human Mcl-1 328 residues - 37715.047 Da.
| 1 | MET | GLU | ASP | GLU | LEU | TYR | ARG | GLN | SER | LEU | ||||
| 2 | GLU | ILE | ILE | SER | ARG | TYR | LEU | ARG | GLU | GLN | ||||
| 3 | ALA | THR | GLY | ALA | LYS | ASP | THR | LYS | PRO | MET | ||||
| 4 | GLY | ARG | SER | GLY | ALA | THR | SER | ARG | LYS | ALA | ||||
| 5 | LEU | GLU | THR | LEU | ARG | ARG | VAL | GLY | ASP | GLY | ||||
| 6 | VAL | GLN | ARG | ASN | HIS | GLU | THR | ALA | PHE | GLN | ||||
| 7 | GLY | MET | LEU | ARG | LYS | LEU | ASP | ILE | LYS | ASN | ||||
| 8 | GLU | ASP | ASP | VAL | LYS | SER | LEU | SER | ARG | VAL | ||||
| 9 | MET | ILE | HIS | VAL | PHE | SER | ASP | GLY | VAL | THR | ||||
| 10 | ASN | TRP | GLY | ARG | ILE | VAL | THR | LEU | ILE | SER | ||||
| 11 | PHE | GLY | ALA | PHE | VAL | ALA | LYS | HIS | LEU | LYS | ||||
| 12 | THR | ILE | ASN | GLN | GLU | SER | SER | ILE | GLU | PRO | ||||
| 13 | LEU | ALA | GLU | SER | ILE | THR | ASP | VAL | LEU | VAL | ||||
| 14 | ARG | THR | LYS | ARG | ASP | TRP | LEU | VAL | LYS | GLN | ||||
| 15 | ARG | GLY | TRP | ASP | GLY | PHE | VAL | GLU | PHE | PHE | ||||
| 16 | HIS | VAL | GLU | ASP | LEU | GLU | GLY | GLY | HIS | HIS | ||||
| 17 | HIS | HIS | HIS | HIS | MET | GLU | ASP | GLU | LEU | TYR | ||||
| 18 | ARG | GLN | SER | LEU | GLU | ILE | ILE | SER | ARG | TYR | ||||
| 19 | LEU | ARG | GLU | GLN | ALA | THR | GLY | ALA | LYS | ASP | ||||
| 20 | THR | LYS | PRO | MET | GLY | ARG | SER | GLY | ALA | THR | ||||
| 21 | SER | ARG | LYS | ALA | LEU | GLU | THR | LEU | ARG | ARG | ||||
| 22 | VAL | GLY | ASP | GLY | VAL | GLN | ARG | ASN | HIS | GLU | ||||
| 23 | THR | ALA | PHE | GLN | GLY | MET | LEU | ARG | LYS | LEU | ||||
| 24 | ASP | ILE | LYS | ASN | GLU | ASP | ASP | VAL | LYS | SER | ||||
| 25 | LEU | SER | ARG | VAL | MET | ILE | HIS | VAL | PHE | SER | ||||
| 26 | ASP | GLY | VAL | THR | ASN | TRP | GLY | ARG | ILE | VAL | ||||
| 27 | THR | LEU | ILE | SER | PHE | GLY | ALA | PHE | VAL | ALA | ||||
| 28 | LYS | HIS | LEU | LYS | THR | ILE | ASN | GLN | GLU | SER | ||||
| 29 | SER | ILE | GLU | PRO | LEU | ALA | GLU | SER | ILE | THR | ||||
| 30 | ASP | VAL | LEU | VAL | ARG | THR | LYS | ARG | ASP | TRP | ||||
| 31 | LEU | VAL | LYS | GLN | ARG | GLY | TRP | ASP | GLY | PHE | ||||
| 32 | VAL | GLU | PHE | PHE | HIS | VAL | GLU | ASP | LEU | GLU | ||||
| 33 | GLY | GLY | HIS | HIS | HIS | HIS | HIS | HIS |
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