BMRB Entry 19474

Name: Structure of uninhibited ETV6 ETS domain
Published: 2013-09-27

Click here to enlarge.

PDB ID: 2md5
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR19474
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

Select model:

I am color blind

Download raw data. Direct link to this display. Help

Title:

Structure of uninhibited ETV6 ETS domain

Deposition date:

2013-08-29

Original release date:

2013-09-27

Authors:

De, Soumya; McIntosh, Lawrence; Chan, Anson; Coyne, Harold; Okon, Mark; Graves, Barbara; Murphy, Michael

Citation:

Citation: De, Soumya; Chan, Anson; Coyne, H. Jerome; Bhachech, Niraja; Hermsdorf, Ulrike; Okon, Mark; Murphy, Michael; Graves, Barbara; McIntosh, Lawrence. "Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6." J. Mol. Biol. ., .-. (2013).
PubMed: 24333486

Assembly members:

Assembly members:
u_ETV6_ETS, polymer, 102 residues, 12450.446 Da.

Natural source:

Natural source: Common Name: house mouse Taxonomy ID: 10090 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Mus musculus

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET 28 a+

Entity Sequences (FASTA):

Entity Sequences (FASTA):
u_ETV6_ETS: GSHMGRIADSRLLWDYVYQL LSDSRYENFIRWEDKESKIF RIVDPNGLARLWGNHKNRTN MTYEKMSRALRHYYKLNIIR KEPGQRLLFRFMKTPDEIMS GR

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
13C chemical shifts	349
15N chemical shifts	101
1H chemical shifts	728

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
Hide all

Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	uninhibited ETV6 ETS domain	1

Entities:

Entity 1, uninhibited ETV6 ETS domain 102 residues - 12450.446 Da.

1

GLY

SER

HIS

MET

GLY

ARG

ILE

ALA

ASP

SER

2

ARG

LEU

TRP

ASP

TYR

VAL

TYR

GLN

LEU

3

LEU

SER

ASP

SER

ARG

TYR

GLU

ASN

PHE

ILE

4

ARG

TRP

GLU

ASP

LYS

GLU

SER

LYS

ILE

PHE

5

ARG

ILE

VAL

ASP

PRO

ASN

GLY

LEU

ALA

ARG

6

LEU

TRP

GLY

ASN

HIS

LYS

ASN

ARG

THR

ASN

7

MET

THR

TYR

GLU

LYS

MET

SER

ARG

ALA

LEU

8

ARG

HIS

TYR

LYS

LEU

ASN

ILE

ARG

9

LYS

GLU

PRO

GLY

GLN

ARG

LEU

PHE

ARG

10

PHE

MET

LYS

THR

PRO

ASP

GLU

ILE

MET

SER

11

GLY

ARG

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aliphatic	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aromatic	sample_1	isotropic	sample_conditions_1
3D H(CCO)NH	sample_1	isotropic	sample_conditions_1
3D (H)CC(CO)NH	sample_1	isotropic	sample_conditions_1
3D HCCH-TOCSY	sample_1	isotropic	sample_conditions_1
3D HNCACB	sample_1	isotropic	sample_conditions_1
3D 1H-15N NOESY	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aliphatic	sample_1	isotropic	sample_conditions_1
2D 1H-13C HSQC aromatic	sample_1	isotropic	sample_conditions_1

PDB	2MD5 4MHG
DBJ	BAC28991 BAC37386 BAE32681 BAE33079 BAE34018
EMBL	CAA69220
GB	AAA19786 AAB17135 AAC97200 AAH43399 AAH52163
REF	NP_001015514 NP_001032430 NP_001186202 NP_001253009 NP_001290031
SP	P41212 P97360 Q0VC65
TPG	DAA29357
AlphaFold	P41212 P97360 Q0VC65

BMRB Entry 19474

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers:

Related Database Links: