BMRB Entry 19385

Chem Shift validation: AVS_anomalous, AVS_full
BMRB Entry DOI: doi:10.13018/BMR19385

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Title:
mu-PIIIA-2
Deposition date:
2013-07-23
Original release date:
2013-08-14
Authors:
Ohlenschlager, Oliver; Tietze, Alesia; Imhof, Diana
Citation:

Citation: Tietze, Alesia; Tietze, Daniel; Ohlenschlager, Oliver; Leipold, Enrico; Ullrich, Florian; Kuhl, Toni; Mischo, Andre; Buntkowsky, Gert; Gorlach, Matthias; Heinemann, Stefan; Imhof, Diana. "Structurally diverse mu-conotoxin PIIIA isomers block sodium channel NaV 1.4"  Angew. Chem. Int. Ed. Engl. 51, 4058-4061 (2012).
PubMed: 22407516

Assembly members:

Assembly members:
conotoxin_muPIIIA-2, polymer, 23 residues, 2603.1 Da.

Natural source:

Natural source:   Common Name: Conus purpurascens   Taxonomy ID: 41690   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus purpurascens

Experimental source:

Experimental source:   Production method: chemical synthesis   Vector: n.a.

Entity Sequences (FASTA):

Entity Sequences (FASTA):
conotoxin_muPIIIA-2: ERLCCGFXKSCRSRQCKXHR CCX

Data sets:
Data typeCount
1H chemical shifts147

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1conotoxin muPIIIA-21

Entities:

Entity 1, conotoxin muPIIIA-2 23 residues - 2603.1 Da.

Residue 1: Pyrrolidone carboxylic acid Residues 8, 18: 4-hydroxyproline Residue 22: cysteine amide

1   GLUARGLEUCYSCYSGLYPHEHYPLYSSER
2   CYSARGSERARGGLNCYSLYSHYPHISARG
3   CYSCYSNH2

Related Database Links:

UNIPROT P58925
NCBI 110282950
BMRB 19384
PDB 1R9I
AlphaFold P58925