BMRB Entry 19125

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR19125

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Title:
Molecular Basis of Histone Acetyllysine Recognition by the BRPF1 Bromodomain.
Deposition date:
2013-03-28
Original release date:
2014-02-12
Authors:
Poplawski, Amanda; Hu, Kaifeng; Lee, Woonghee; Peng, Danni; Carlson, Samuel; Neuhardt, Elizabeth; Shi, Xiaobing; Markley, John; Glass, Karen
Citation:

Citation: Poplawski, Amanda; Hu, Kaifeng; Lee, Woonghee; Natesan, Senthil; Peng, Danni; Carlson, Samuel; Shi, Xiaobing; Balaz, Stefan; Markley, John; Glass, Karen. "Molecular Insights into the Recognition of N-Terminal Histone Modifications by the BRPF1 Bromodomain."  J. Mol. Biol. 426, 1661-1676 (2014).
PubMed: 24333487

Assembly members:

Assembly members:
BRPF1_bromodomain, polymer, 117 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pDEST15

Entity Sequences (FASTA):

Entity Sequences (FASTA):
BRPF1_bromodomain: GPLQLTPFLILLRKTLEQLQ EKDTGNIFSEPVPLSEVPDY LDHIKKPMDFFTMKQNLEAY RYLNFDDFEEDFNLIVSNCL KYNAKDTIFYRAAVRLREQG GAVLRQARRQAEKMGID

Data sets:
Data typeCount
13C chemical shifts317
15N chemical shifts99
1H chemical shifts99

Additional metadata:

  • Assembly
  • Samples and Experiments
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Assembly:

Entity Assembly IDEntity NameEntity ID
1BRPF11

Entities:

Entity 1, BRPF1 117 residues - Formula weight is not available

1   GLYPROLEUGLNLEUTHRPROPHELEUILE
2   LEULEUARGLYSTHRLEUGLUGLNLEUGLN
3   GLULYSASPTHRGLYASNILEPHESERGLU
4   PROVALPROLEUSERGLUVALPROASPTYR
5   LEUASPHISILELYSLYSPROMETASPPHE
6   PHETHRMETLYSGLNASNLEUGLUALATYR
7   ARGTYRLEUASNPHEASPASPPHEGLUGLU
8   ASPPHEASNLEUILEVALSERASNCYSLEU
9   LYSTYRASNALALYSASPTHRILEPHETYR
10   ARGALAALAVALARGLEUARGGLUGLNGLY
11   GLYALAVALLEUARGGLNALAARGARGGLN
12   ALAGLULYSMETGLYILEASP

Related Database Links:

PDB 4LC2 4QYD 4QYL 4UYE 5C7N
DBJ BAC31528 BAE33691 BAG10583 BAG57257
EMBL CAD28495
GB AAB02119 AAF19605 AAH05647 AAH46521 AAI38362
REF NP_001178501 NP_001269055 NP_001269056 NP_004625 NP_084454
SP P55201
TPG DAA17219
AlphaFold P55201

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