BMRB Entry 18964

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PDB ID: 2m3i
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18964
MolProbity Validation Chart

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Title:
Characterization of a Novel Alpha4/6-Conotoxin TxIC from Conus textile that Potently Blocks alpha3beta4 Nicotinic Acetylcholine Receptors
Deposition date:
2013-01-20
Original release date:
2013-12-20
Authors:
Luo, Sulan; Zhangsun, Dongting; Zhu, Xiaopeng; Wu, Yong; Hu, Yuanyan; Christensen, Sean; Akcan, Muharrem; Craik, David; McIntosh, J. Michael
Citation:

Citation: Luo, Sulan; Zhangsun, Dongting; Zhu, Xiaopeng; Wu, Yong; Hu, Yuanyan; Christensen, Sean; Harvey, Peta; Akcan, Muharrem; Craik, David; McIntosh, J. Michael. "Characterization of a Novel -Conotoxin TxID from Conus textile That Potently Blocks Rat 34 Nicotinic Acetylcholine Receptors."  J. Med. Chem. 56, 9655-9663 (2013).
PubMed: 24200193

Assembly members:

Assembly members:
TxIC, polymer, 16 residues, 1493.806 Da.

Natural source:

Natural source:   Common Name: Cloth-of-gold Cone   Taxonomy ID: 6494   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Conus Textile

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
TxIC: GCCSHPVCSAMSPICX

Data sets:
Data typeCount
1H chemical shifts77

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1Novel Alpha4/6-Conotoxin TxIC1

Entities:

Entity 1, Novel Alpha4/6-Conotoxin TxIC 16 residues - 1493.806 Da.

1   GLYCYSCYSSERHISPROVALCYSSERALA
2   METSERPROILECYSNH2

Related Database Links:

PDB 2M3I
EMBL CCN27219
GB AFD18484