BMRB Entry 18908

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PDB ID: 2m2d
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR18908
MolProbity Validation Chart

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Title:
Human programmed cell death 1 receptor
Deposition date:
2012-12-18
Original release date:
2013-02-21
Authors:
Veverka, Vaclav; Cheng, Xiaoxiao; Waters, Lorna; Muskett, Frederick; Morgan, Sara; Lesley, Alastair; Griffiths, Merryn; Stubberfield, Colin; Griffin, Robert; Henry, Alistair; Robinson, Martyn; Jansson, Andreas; Ladbury, John; Ikemizu, Shinji; Davis, Simon; Carr, Mark
Citation:

Citation: Cheng, Xiaoxiao; Veverka, Vaclav; Radhakrishnan, Anand; Waters, Lorna; Muskett, Frederick; Morgan, Sara; Huo, Jiandong; Yu, Chao; Evans, Edward; Leslie, Alasdair; Griffiths, Meryn; Stubberfield, Colin; Griffin, Robert; Henry, Alistair; Jansson, Andreas; Ladbury, John; Ikemizu, Shinji; Carr, Mark; Davis, Simon. "Structure and interactions of the human programmed cell death 1 receptor."  J. Biol. Chem. 288, 11771-11785 (2013).
PubMed: 23417675

Assembly members:

Assembly members:
Human programmed cell death 1 receptor, polymer, 118 residues, 13245.914 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET

Entity Sequences (FASTA):

Entity Sequences (FASTA):
Human programmed cell death 1 receptor: MPPTFSPALLVVTEGDNATF TCSFSNTSESFVLNWYRMSP SNQTDKLAAFPEDRSQPGQD SRFRVTQLPNGRDFHMSVVR ARRNDSGTYLCGAISLAPKA QIKESLRAELRVTERRAE

Data sets:
Data typeCount
13C chemical shifts453
15N chemical shifts119
1H chemical shifts774

Additional metadata:

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Assembly:

Entity Assembly IDEntity NameEntity ID
1Human programmed cell death 1 receptor1

Entities:

Entity 1, Human programmed cell death 1 receptor 118 residues - 13245.914 Da.

1   METPROPROTHRPHESERPROALALEULEU
2   VALVALTHRGLUGLYASPASNALATHRPHE
3   THRCYSSERPHESERASNTHRSERGLUSER
4   PHEVALLEUASNTRPTYRARGMETSERPRO
5   SERASNGLNTHRASPLYSLEUALAALAPHE
6   PROGLUASPARGSERGLNPROGLYGLNASP
7   SERARGPHEARGVALTHRGLNLEUPROASN
8   GLYARGASPPHEHISMETSERVALVALARG
9   ALAARGARGASNASPSERGLYTHRTYRLEU
10   CYSGLYALAILESERLEUALAPROLYSALA
11   GLNILELYSGLUSERLEUARGALAGLULEU
12   ARGVALTHRGLUARGARGALAGLU

Related Database Links:

PDB 2M2D 3RRQ 4ZQK
DBJ BAG36577 BAJ21104
GB AAC41700 AAC51773 AAH74740 AAN64003 AAO25116
REF NP_005009 XP_003776178 XP_004033550 XP_006712636 XP_006725049
SP Q15116
AlphaFold Q15116

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