BMRB Entry 18608

Name: Backbone resonance assignment of ASC pyrin domain
Published: 2012-10-18

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18608

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Nicholas Rego and David Koes
3Dmol.js: molecular visualization with WebGL
Bioinformatics (2015) 31 (8): 1322-1324 doi:10.1093/bioinformatics/btu829

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Title:

Backbone resonance assignment of ASC pyrin domain

Deposition date:

2012-07-23

Original release date:

2012-10-18

Authors:

Vajjhala, Parimala; Mirams, Ruth; Hill, Justine

Citation:

Citation: Vajjhala, Parimala; Mirams, Ruth; Hill, Justine. "Multiple binding sites on the pyrin domain of ASC protein allow self-association and interaction with NLRP3 protein." J. Biol. Chem. 287, 41732-41743 (2012).
PubMed: 23066025

Assembly members:

Assembly members:
ASC_PYD, polymer, 108 residues, Formula weight is not available

Natural source:

Natural source: Common Name: Human Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens

Experimental source:

Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pQE-30

Entity Sequences (FASTA):

Entity Sequences (FASTA):
ASC_PYD: MRGSHHHHHHGSMGRARDAI LDALENLTAEELKKFKLKLL SVPLREGYGRIPRGALLSMD SLDLTDKLVSFYLETYGAEL TANVLRDMGLQEMAGQLQAA THQGSGAA

Data sets:

assigned_chemical_shifts
- assigned_chem_shift_list_1

Data type	Count
13C chemical shifts	266
15N chemical shifts	89
1H chemical shifts	88

Additional metadata:

Assembly
Samples and Experiments
Software
Spectrometers
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Assembly:

Entity Assembly ID	Entity Name	Entity ID
1	ASC PYD	1

Entities:

Entity 1, ASC PYD 108 residues - Formula weight is not available

1

MET

ARG

GLY

SER

HIS

2

GLY

SER

MET

GLY

ARG

ALA

ARG

ASP

ALA

ILE

3

LEU

ASP

ALA

LEU

GLU

ASN

LEU

THR

ALA

GLU

4

GLU

LEU

LYS

PHE

LYS

LEU

LYS

LEU

5

SER

VAL

PRO

LEU

ARG

GLU

GLY

TYR

GLY

ARG

6

ILE

PRO

ARG

GLY

ALA

LEU

SER

MET

ASP

7

SER

LEU

ASP

LEU

THR

ASP

LYS

LEU

VAL

SER

8

PHE

TYR

LEU

GLU

THR

TYR

GLY

ALA

GLU

LEU

9

THR

ALA

ASN

VAL

LEU

ARG

ASP

MET

GLY

LEU

10

GLN

GLU

MET

ALA

GLY

GLN

LEU

GLN

ALA

11

THR

HIS

GLN

GLY

SER

GLY

ALA

Name	Sample	Sample state	Sample conditions
2D 1H-15N HSQC	sample_1	isotropic	sample_conditions_1
3D HNCO	sample_2	isotropic	sample_conditions_1
3D HNCACB	sample_2	isotropic	sample_conditions_1
3D HN(CA)CO	sample_2	isotropic	sample_conditions_1
3D CBCA(CO)NH	sample_2	isotropic	sample_conditions_1

PDB	1UCP 3J63
DBJ	BAA87339 BAG37041 BAG73625
GB	AAF99665 AAG01187 AAG01188 AAG30286 AAH13569
REF	NP_037390 NP_660183 XP_001158625 XP_001158687 XP_003280507
SP	Q9ULZ3
AlphaFold	Q9ULZ3

BMRB Entry 18608

Additional metadata:

Assembly:

Entities:

Samples:

Experiments:

Software:

NMR spectrometers:

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