BMRB Entry 18559
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PDB ID: 2lv9
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR18559
MolProbity Validation Chart
NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
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Citation: Lemak, Alexander; Yee, Adelinda; Wu, Hong; Yap, Damian; Zeng, Hong; Dombrovski, Ludmila; Houliston, Scott; Aparicio, Samuel; Arrowsmith, Cheryl. "Solution NMR structure and histone binding of the PHD domain of human MLL5." PLoS ONE 8, e77020-e77020 (2013).
PubMed: 24130829
Assembly members:
MLL5, polymer, 98 residues, 9318.508 Da.
ZINC ION, non-polymer, 65.409 Da.
Natural source: Common Name: Humans Taxonomy ID: 9606 Superkingdom: Eukaryota Kingdom: Metazoa Genus/species: Homo sapiens
Experimental source: Production method: recombinant technology Host organism: Escherichia coli Vector: pET28b
Entity Sequences (FASTA):
MLL5: MHHHHHHSSGRENLYFQGSE
DGSYGTDVTRCICGFTHDDG
YMICCDKCSVWQHIDCMGID
RQHIPDTYLCERCQPRNLDK
ERAVLLQRRKRENMSDGD
- assigned_chemical_shifts
| Data type | Count |
| 13C chemical shifts | 298 |
| 15N chemical shifts | 74 |
| 1H chemical shifts | 472 |
Additional metadata:
Assembly:
| Entity Assembly ID | Entity Name | Entity ID |
|---|---|---|
| 1 | MLL5 | 1 |
| 2 | ZINC ION_1 | 2 |
| 3 | ZINC ION_2 | 2 |
Entities:
Entity 1, MLL5 98 residues - 9318.508 Da.
| 1 | MET | HIS | HIS | HIS | HIS | HIS | HIS | SER | SER | GLY | ||||
| 2 | ARG | GLU | ASN | LEU | TYR | PHE | GLN | GLY | SER | GLU | ||||
| 3 | ASP | GLY | SER | TYR | GLY | THR | ASP | VAL | THR | ARG | ||||
| 4 | CYS | ILE | CYS | GLY | PHE | THR | HIS | ASP | ASP | GLY | ||||
| 5 | TYR | MET | ILE | CYS | CYS | ASP | LYS | CYS | SER | VAL | ||||
| 6 | TRP | GLN | HIS | ILE | ASP | CYS | MET | GLY | ILE | ASP | ||||
| 7 | ARG | GLN | HIS | ILE | PRO | ASP | THR | TYR | LEU | CYS | ||||
| 8 | GLU | ARG | CYS | GLN | PRO | ARG | ASN | LEU | ASP | LYS | ||||
| 9 | GLU | ARG | ALA | VAL | LEU | LEU | GLN | ARG | ARG | LYS | ||||
| 10 | ARG | GLU | ASN | MET | SER | ASP | GLY | ASP |
Entity 2, ZINC ION_1 - Zn - 65.409 Da.
| 1 | ZN |
Related Database Links:
| PDB | 2LV9 4L58 |
| DBJ | BAE28389 BAE35839 BAE43262 BAE88379 |
| EMBL | CAH93210 |
| GB | AAD04721 AAF75564 AAH01296 AAH36286 AAH62583 |
| REF | NP_001075920 NP_001094321 NP_061152 NP_081260 NP_891847 |
| SP | Q3UG20 Q8IZD2 |
| TPG | DAA30676 |
| AlphaFold | Q3UG20 Q8IZD2 |
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SPARKY: Backbone
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