BMRB Entry 17752

Click here to enlarge.

PDB ID: 2lfg
Entry in NMR Restraints Grid
Validation report in NRG-CING
Chem Shift validation: AVS_anomalous, AVS_full, LACS, SPARTA
BMRB Entry DOI: doi:10.13018/BMR17752
MolProbity Validation Chart

NMR-STAR file interactive viewer.
NMR-STAR v3 text file.
XML gzip file.
RDF gzip file.
All files associated with the entry

Title:
SOLUTION STRUCTURE OF THE HUMAN PROLACTIN RECEPTOR ECD DOMAIN D2
Deposition date:
2011-06-30
Original release date:
2012-02-13
Authors:
Dagil, Robert; Knudsen, Maiken; Kragelund, Birthe; O'Shea, Charlotte
Citation:

Citation: Dagil, Robert; Knudsen, Maiken; Olsen, Johan; O'Shea, Charlotte; Franzmann, Magnus; Goffin, Vincent; Teilum, Kaare; Breinholt, Jens; Kragelund, Birthe. "The WSXWS Motif in Cytokine Receptors Is a Molecular Switch Involved in Receptor Activation: Insight from Structures of the Prolactin Receptor"  Structure 20, 270-282 (2012).

Assembly members:

Assembly members:
hPRLR-D2, polymer, 113 residues, 13328.4 Da.

Natural source:

Natural source:   Common Name: Human   Taxonomy ID: 9606   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Homo sapiens

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET11A

Entity Sequences (FASTA):

Entity Sequences (FASTA):
hPRLR-D2: MYIVQPDPPLELAVEVKQPE DRKPYLWIKWSPPTLIDLKT GWFTLLYEIRLKPEKAAEWE IHFAGQQTEFKILSLHPGQK YLVQVRCKPDHGYWSAWSPA TFIQIPSDFTMND

Data sets:
Data typeCount
13C chemical shifts549
15N chemical shifts112
1H chemical shifts809

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1hPRLR-D21

Entities:

Entity 1, hPRLR-D2 113 residues - 13328.4 Da.

1   METTYRILEVALGLNPROASPPROPROLEU
2   GLULEUALAVALGLUVALLYSGLNPROGLU
3   ASPARGLYSPROTYRLEUTRPILELYSTRP
4   SERPROPROTHRLEUILEASPLEULYSTHR
5   GLYTRPPHETHRLEULEUTYRGLUILEARG
6   LEULYSPROGLULYSALAALAGLUTRPGLU
7   ILEHISPHEALAGLYGLNGLNTHRGLUPHE
8   LYSILELEUSERLEUHISPROGLYGLNLYS
9   TYRLEUVALGLNVALARGCYSLYSPROASP
10   HISGLYTYRTRPSERALATRPSERPROALA
11   THRPHEILEGLNILEPROSERASPPHETHR
12   METASNASP

Related Database Links:

PDB 1BP3 2LFG 3D48 3MZG 3N06 3N0P 3NCB 3NCC 3NCE 3NCF 4I18
DBJ BAG36079 BAG73583
EMBL CAH91100 CAL38328 CAL38451
GB AAA60174 AAB34470 AAD32032 AAD49855 AAH59392
REF NP_000940 NP_001153263 NP_001191243 NP_001191244 NP_001191245
SP P16471
AlphaFold P16471

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks