BMRB Entry 17748

Chem Shift validation: AVS_full, LACS
BMRB Entry DOI: doi:10.13018/BMR17748

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Title:
Solution NMR Insights into Docking Interactions Involving Inactive ERK2
Deposition date:
2011-06-29
Original release date:
2011-07-18
Authors:
Piserchio, Andrea; Ghose, Ranajeet
Citation:

Citation: Piserchio, Andrea; Warthaka, Mangalika; Devkota, Ashwini; Kaoud, Tamer; Lee, Sunbae; Abramczyk, Olga; Ren, Pengyu; Dalby, Kevin; Ghose, Ranajeet. "Solution NMR Insights into Docking Interactions Involving Inactive ERK2."  Biochemistry 50, 3660-3672 (2011).
PubMed: 21449613

Assembly members:

Assembly members:
ERK2, polymer, 361 residues, Formula weight is not available

Natural source:

Natural source:   Common Name: Rat   Taxonomy ID: 10116   Superkingdom: Eukaryota   Kingdom: Metazoa   Genus/species: Rattus norvegicus

Experimental source:

Experimental source:   Production method: recombinant technology   Host organism: Escherichia coli   Vector: pET28

Entity Sequences (FASTA):

Entity Sequences (FASTA):
ERK2: GSHMAAAAAAGPEMVRGQVF DVGPRYTNLSYIGEGAYGMV CSAYDNLNKVRVAIKKISPF EHQTYCQRTLREIKILLRFR HENIIGINDIIRAPTIEQMK DVYIVQDLMETDLYKLLKTQ HLSNDHICYFLYQILRGLKY IHSANVLHRDLKPSNLLLNT TCDLKICDFGLARVADPDHD HTGFLTEYVATRWYRAPEIM LNSKGYTKSIDIWSVGCILA EMLSNRPIFPGKHYLDQLNH ILGILGSPSQEDLNCIINLK ARNYLLSLPHKNKVPWNRLF PNADSKALDLLDKMLTFNPH KRIEVEQALAHPYLEQYYDP SDEPIAEAPFKFDMELDDLP KEKLKELIFEETARFQPGYR S

Data sets:
Data typeCount
13C chemical shifts569
15N chemical shifts186
1H chemical shifts186

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
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Assembly:

Entity Assembly IDEntity NameEntity ID
1ERK21

Entities:

Entity 1, ERK2 361 residues - Formula weight is not available

1   GLYSERHISMETALAALAALAALAALAALA
2   GLYPROGLUMETVALARGGLYGLNVALPHE
3   ASPVALGLYPROARGTYRTHRASNLEUSER
4   TYRILEGLYGLUGLYALATYRGLYMETVAL
5   CYSSERALATYRASPASNLEUASNLYSVAL
6   ARGVALALAILELYSLYSILESERPROPHE
7   GLUHISGLNTHRTYRCYSGLNARGTHRLEU
8   ARGGLUILELYSILELEULEUARGPHEARG
9   HISGLUASNILEILEGLYILEASNASPILE
10   ILEARGALAPROTHRILEGLUGLNMETLYS
11   ASPVALTYRILEVALGLNASPLEUMETGLU
12   THRASPLEUTYRLYSLEULEULYSTHRGLN
13   HISLEUSERASNASPHISILECYSTYRPHE
14   LEUTYRGLNILELEUARGGLYLEULYSTYR
15   ILEHISSERALAASNVALLEUHISARGASP
16   LEULYSPROSERASNLEULEULEUASNTHR
17   THRCYSASPLEULYSILECYSASPPHEGLY
18   LEUALAARGVALALAASPPROASPHISASP
19   HISTHRGLYPHELEUTHRGLUTYRVALALA
20   THRARGTRPTYRARGALAPROGLUILEMET
21   LEUASNSERLYSGLYTYRTHRLYSSERILE
22   ASPILETRPSERVALGLYCYSILELEUALA
23   GLUMETLEUSERASNARGPROILEPHEPRO
24   GLYLYSHISTYRLEUASPGLNLEUASNHIS
25   ILELEUGLYILELEUGLYSERPROSERGLN
26   GLUASPLEUASNCYSILEILEASNLEULYS
27   ALAARGASNTYRLEULEUSERLEUPROHIS
28   LYSASNLYSVALPROTRPASNARGLEUPHE
29   PROASNALAASPSERLYSALALEUASPLEU
30   LEUASPLYSMETLEUTHRPHEASNPROHIS
31   LYSARGILEGLUVALGLUGLNALALEUALA
32   HISPROTYRLEUGLUGLNTYRTYRASPPRO
33   SERASPGLUPROILEALAGLUALAPROPHE
34   LYSPHEASPMETGLULEUASPASPLEUPRO
35   LYSGLULYSLEULYSGLULEUILEPHEGLU
36   GLUTHRALAARGPHEGLNPROGLYTYRARG
37   SER

Related Database Links:

PDB 1ERK 1GOL 1PME 1TVO 1WZY 2ERK 2FYS 2GPH 2OJG 2OJI 2OJJ 2Y9Q 2Z7L 3C9W 3ERK 3I5Z 3I60 3O71 3QYW 3QYZ 3R63 3SA0 3TEI 3W55 3ZU7 3ZUV 4ERK 4FMQ 4FUX 4FUY 4FV0 4FV1 4FV2 4FV3 4FV4 4FV5 4FV6 4FV7 4FV8 4FV9 4G6N 4G6O 4GSB 4GT3 4GVA 4H3P 4H3Q 4I5H 4IZ5 4IZ7 4IZA 4N0S 4N4S 4NIF 4O6E 4QP1 4QP2 4QP3 4QP4 4QP6 4QP7 4QP8 4QP9 4QPA 4QTA 4QTE 4QYY 4XJ0 4XNE 4XOY 4XOZ 4XP0 4XP2 4XP3 4XRJ 4ZZM 4ZZN 4ZZO 5BUE 5BUI 5BUJ 5BVD 5BVE 5BVF
DBJ BAA01733 BAA22620 BAC29053 BAC33251 BAC40044
EMBL CAA41548 CAA77752 CAA77753 CAA78467 CAI29602
GB AAA41124 AAA58459 AAH17832 AAH58258 AAH99905
PRF 1813206A 1813206B
REF NP_001033752 NP_001104270 NP_001185851 NP_001297736 NP_001301131
SP P28482 P46196 P63085 P63086
TPG DAA20381
AlphaFold P28482 P46196 P63085 P63086

Download HSQC peak lists in one of the following formats:
CSV: Backbone or all simulated peaks
SPARKY: Backbone or all simulated peaks